Pharmacological management of neuropathic pain

G McCleane - CNS drugs, 2003 - Springer
… Given the widespread use of tramadol and its derivatives, and the evidence of its analgesic
effect in some varieties of neuropathic pain, the author of this review believes that it is …

Neuropathic pain

LA Zilliox - CONTINUUM: Lifelong Learning in Neurology, 2017 - journals.lww.com
… The analgesic effect of tricyclic antidepressants is independent of their antidepressant effect,
and the analgesic effect is … by much lower doses in comparison to the antidepressant effect. …

Neuropathic pain: mechanisms and their clinical implications

SP Cohen, J Mao - Bmj, 2014 - bmj.com
… One reason for the high prevalence rate of chronic pain, and neuropathic pain in particular,
pain, the adjuvants used to treat neuropathic pain tend to have only a modest effect and in a …

Potent analgesic effects of GDNF in neuropathic pain states

TJ Boucher, K Okuse, DLH Bennett, JB Munson… - Science, 2000 - science.org
… Such pains are often intense, persistent, and refractory to existing analgesic therapy. Here,
we … in animal models of neuropathic pain and have studied putative mechanisms of action. …

Botulinum toxin type A induces direct analgesic effects in chronic neuropathic pain

D Ranoux, N Attal, F Morain… - Annals of Neurology …, 2008 - Wiley Online Library
… The efficacy of BTX-A in neuropathic pain has been … analgesic effects of one-time BTX-A
in the painful area in patients with focal neuropathic pain (eg, posttraumatic/postoperative pain

Understanding neuropathic pain

W Zieglgänsberger, A Berthele, TR Tölle - CNS spectrums, 2005 - cambridge.org
… , nerve entrapment, or painful neuropathy, from immune … of neuropathic pain has come from
animal models of painful periph… These studies have shown that neuropathic pain is probably …

[PDF][PDF] Opioids and neuropathic pain

HS Smith - Pain physician, 2012 - painphysicianjournal.com
… NP is less responsive to the analgesic effects of opioids than spinal central NP (16) (Fig. 1). …
Increased NMDA activity did not alter the normal morphine analgesic effect. Although NMDA …

Opioids in neuropathic pain

R Przewlocki, B Przewlocka - Current pharmaceutical design, 2005 - ingentaconnect.com
… Therefore, the reduced analgesic effect of morphine in neuropathic pain may be due to
impairment of µ-opioid receptor-G protein coupling rather than reduction in µ-opioid receptor …

Analgesic effect of dextromethorphan in neuropathic pain

KC Carlsson, NO Hoem, ER Moberg… - Acta …, 2004 - Wiley Online Library
… better analgesic effect than poor … an analgesic effect in patients with neuropathic pain of
traumatic origin. The main metabolite dextrorphan seems to be important for the analgesic effect. …

Neuropathic pain: a clinical perspective

R Baron - Sensory Nerves, 2009 - Springer
… At present existing trials only provide general pain relief values for specific causes, which in
pain relief in neuropathic pain conditions. In general, the treatment of neuropathic pain is still …