The role of the immune system in the generation of neuropathic pain

M Calvo, JM Dawes, DLH Bennett - The lancet neurology, 2012 - thelancet.com
… by these immune cells directly … immune response to neural injury in animal models. We
assess the clinical evidence for an aberrant immune response contributing to neuropathic pain

Immune and inflammatory mechanisms in neuropathic pain

G Moalem, DJ Tracey - Brain research reviews, 2006 - Elsevier
… In addition, the immune response plays an important role in demyelinating neuropathies
such … us to understand the role of inflammatory and immune mechanisms in neuropathic pain. …

[HTML][HTML] Role of the immune system in neuropathic pain

M Malcangio - Scandinavian journal of pain, 2019 - degruyter.com
… An emerging concept in the pain research area is that the immune response associated
with damage in the central nervous system (CNS) and peripheral nervous system (PNS) may …

Pathophysiology of peripheral neuropathic pain: immune cells and molecules

MA Thacker, AK Clark, F Marchand… - Anesthesia & …, 2007 - journals.lww.com
immune cells play a role in neuropathic pain in the periphery. In this review we identify the
different immune cell types that contribute to neuropathic pain in … peripheral immune response

Pain-resolving immune mechanisms in neuropathic pain

NT Fiore, SR Debs, JP Hayes, SS Duffy… - Nature Reviews …, 2023 - nature.com
… Initially considered as passive bystanders, then as culprits in the pathogenesis of neuropathic
pain, immune responses in the nervous system are now established to underpin not only …

Neuropathic pain and cytokines: current perspectives

AK Clark, EA Old, M Malcangio - Journal of pain research, 2013 - Taylor & Francis
… nociceptive transmission under conditions of neuropathic pain. Here we review the … response
that the host organizes to counteract foreign insults; they drive the innate immune response

[HTML][HTML] Neuropathic pain: role of inflammation, immune response, and ion channel activity in central injury mechanisms

D Schomberg, M Ahmed, G Miranpuri… - Annals of …, 2012 - ncbi.nlm.nih.gov
Immune Response Growing evidence is implicating a significant role of the immune response
in the development of neuropathic pain, particularly through the activity of immune cells …

[HTML][HTML] The immune aspect in neuropathic pain: role of chemokines

JT Liou, CM Lee, YJ Day - Acta Anaesthesiologica Taiwanica, 2013 - Elsevier
… in neuropathic pain models remained controversial. To observe the difference in immune
responses and … Our findings demonstrated attenuated inflammatory responses and behavioral …

The role of glia and the immune system in the development and maintenance of neuropathic pain

R Vallejo, DM Tilley, L Vogel, R Benyamin - Pain practice, 2010 - Wiley Online Library
… only expressed to facilitate the localization of the immune response around the site of
injury or infection. Numerous rodent neuropathic pain models have demonstrated an up-regulation …

The neuropathic pain triad: neurons, immune cells and glia

J Scholz, CJ Woolf - Nature neuroscience, 2007 - nature.com
… for neuropathic pain and produce undesirable side effects 1 . Neuropathic pain management
… In contrast, modulating the immune response to nerve injury and targeting glia may provide …