… reactions in a neuropathic pain model. For this purpose, we investigated the effects of specific
δ 1 - and δ 2 -opioid receptor agonists and antagonists in a neuropathic pain model after …

… -opioid receptor agonists, which suggests that both δ-opioid receptor subtypes play a similar
role in neuropathic pain… Thus, both δ1- and δ2-opioid receptor agonists can be regarded as …

… Because sustained activation of opioid receptors might induce tolerance, we measured
the antinociceptive effect of the κ agonist U50,488 using radiant heat applied to the ipsilateral …

… NP states involving downregulation or desensitization of μ-opioid receptors. Functional
downregulation and/or desensitization of μ-opioid receptors in the dorsal horn of the spinal cord (…

… both NP groups may reflect endogenous opioid release secondary to chronic pain, the more
… suggests opioid receptor loss or inactivation in receptor-bearing neurons. Opioid binding …

… of receptors without the loss of the total number of receptors [… opioid receptors concerning
NP to highlight the role of opioid receptors and to explain the poor therapeutic effect of opioids…

… of δ-opioid receptor (DOR) in the development and expression of neuropathic pain. For this
purpose, … In wild-type and DOR knockout mice, sciatic nerve injury led to a neuropathic pain …

… their effects in neuropathic pain. In this study, we investigated the anti-allodynic effects of
peripherally acting delta opioid receptor (DOR) agonists in a rat model of neuropathic pain. …

… Since the downregulation of μ‐opioid receptors is observed in dorsal spinal cord, morphine
… the course neuropathic pain states. The downregulation of μ‐opioid receptors is suggested …

… the μ-opioid receptors. Identification of the differences between these μ-opioid receptor agonists
… importance to our understanding of the mechanism of opioid action in neuropathic pain. …