The role of the dorsal root ganglion in the development of neuropathic pain

ES Krames - Pain Medicine, 2014 - academic.oup.com
… The dorsal root ganglion (DRG), in the not too distant past, had been thought of as a passive
organ not involved in the development of abnormal aberrent neuropathic pain (NP), but …

The dorsal root ganglion in the pathogenesis of chronic neuropathic pain

D Guha, MF Shamji - Neurosurgery, 2016 - journals.lww.com
… is a syndrome of disordered sensory perception in which pain is felt … neuropathic pain; third,
the cellular, molecular, and genetic alterations in the DRG associated with neuropathic pain; …

Dorsal root ganglion–a potential new therapeutic target for neuropathic pain

D Sapunar, S Kostic, A Banozic, L Puljak - Journal of pain research, 2012 - Taylor & Francis
… in sensory ganglia. Damage to the axons of sensory ganglia contributes to neuropathic
pain. … SGCs so these cells have a role in the pathological changes in the ganglia. Citation18 …

Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?

W Wang, J Gu, YQ Li, YX Tao - Molecular pain, 2011 - journals.sagepub.com
root ganglion. We also review evidence regarding changes in their expression under
neuropathic pain conditions and their roles in behavioral responses in a variety of neuropathic pain

Identification of gene expression profile of dorsal root ganglion in the rat peripheral axotomy model of neuropathic pain

HS Xiao, QH Huang, FX Zhang, L Bao… - Proceedings of the …, 2002 - National Acad Sciences
… Phenotypic modification of dorsal root ganglion (DRG) neurons represents an important
mechanism underlying neuropathic pain. However, the nerve injury-induced molecular changes …

Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain

X Yu, H Liu, KA Hamel, MG Morvan, S Yu, J Leff… - Nature …, 2020 - nature.com
… to nerve injury-induced neuropathic pain 21 . However, their … , had limited impact on
neuropathic pain development 6 . … macrophage contribution to the neuropathic pain phenotype. …

Electrophysiological and transcriptomic correlates of neuropathic pain in human dorsal root ganglion neurons

RY North, Y Li, P Ray, LD Rhines, CE Tatsui, G Rao… - Brain, 2019 - academic.oup.com
… Determination of presence or absence of radicular/neuropathic pain was performed for …
dorsal root ganglion and consistent with the guidelines for probable or definite neuropathic pain

The efficacy and safety of dorsal root ganglion stimulation as a treatment for neuropathic pain: a literature review

C Harrison, S Epton, S Bojanic, AL Green… - … : technology at the …, 2018 - Elsevier
… summarized the literature to date on the use of DRGS in the treatment of neuropathic pain. …
complete understanding of the role of DRGS in the treatment of neuropathic pain syndromes. …

Membrane potential oscillations in dorsal root ganglion neurons: role in normal electrogenesis and neuropathic pain

R Amir, M Michaelis, M Devor - Journal of Neuroscience, 1999 - Soc Neuroscience
… , dysaesthesias, and chronic neuropathic pain. We report here … neurons in excised rat dorsal
root ganglia, we found that some … of controlling neuropathic paraesthesias and pain without …

One-year outcomes of spinal cord stimulation of the dorsal root ganglion in the treatment of chronic neuropathic pain

L Liem, M Russo, FJPM Huygen, JP Van Buyten… - … : Technology at the …, 2015 - Elsevier
… of the dorsal root ganglion (DRG-SCS) is a new therapy for treating chronic neuropathic
pain. Previous work has demonstrated the effectiveness of DRG-SCS for pain associated with …