Effect of TRPV4‐p38 MAPK pathway on neuropathic pain in rats with chronic compression of the dorsal root ganglion

YJ Qu, X Zhang, ZZ Fan, J Huai… - BioMed Research …, 2016 - Wiley Online Library
… To study the effects of TRPV4 and p38 with regard to neuropathic pain further, we sought
to determine the abilities of RR, 4α-PDD, SB203580, and anisomycin to enhance or block the …

Effect of artemisinin on neuropathic pain mediated by P2X4 receptor in dorsal root ganglia

M Ying, H Liu, T Zhang, C Jiang, Y Gong, B Wu… - Neurochemistry …, 2017 - Elsevier
… This study tested whether artemisinin could influence pain behavior in a neuropathic pain
rat model, and it assessed the possible mechanism of artemisinin acting on neuropathic pain

[HTML][HTML] Chronic nerve injury-induced Mas receptor expression in dorsal root ganglion neurons alleviates neuropathic pain

Y Zhao, Y Qin, T Liu, D Hao - Experimental and …, 2015 - spandidos-publications.com
… and aggravate CCI‑induced neuropathic pain, respectively. This … neuropathic pain and
suggests that the Ang‑(1‑7)/Mas axis could be an effective therapeutic target for neuropathic pain

Sigma-1 receptors control neuropathic pain and macrophage infiltration into the dorsal root ganglion after peripheral nerve injury

I Bravo Caparrós, MC Ruiz Cantero, G Perazzoli… - 2020 - digibug.ugr.es
root ganglia (DRG) plays a pivotal role in neuropathic pain … neurons but its role in neuropathic
pain is not fully understood. … and less IL-6 and neuropathic mechanical allodynia after SNI. …

The protective effect of resveratrol in the transmission of neuropathic pain mediated by the P2X7 receptor in the dorsal root ganglia

J Xie, S Liu, B Wu, G Li, S Rao, L Zou, Z Yi… - Neurochemistry …, 2017 - Elsevier
… is related to chronic neuropathic pain. Resveratrol (RES) … neuropathic pain mediated by the
P2X 7 receptor. The P2X 7 mRNA and protein expression levels in L4-L5 dorsal root ganglia (…

Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain

I Obara, JR Parkitna, M Korostynski, W Makuch… - Pain, 2009 - journals.lww.com
… in neuropathic pain, we analyzed the abundance of opioid transcripts in the spinal cord and
dorsal root ganglia (DRG) during the neuropathy … administered opioids in neuropathy. The …

Spontaneous discharge originates in the dorsal root ganglion at the onset of a painful peripheral neuropathy in the rat

KC Kajander, S Wakisaka, GJ Bennett - Neuroscience letters, 1992 - Elsevier
… sciatic nerve and the dorsal root were determined, as were … of the nerve and the dorsal root
ganglion (DRG). Transections … neuropathic pain syndrome appear to originate in the DRG. …

Neuropathic pain is associated with alterations of nitric oxide synthase immunoreactivity and catalytic activity in dorsal root ganglia and spinal dorsal horn

D Čı́žková, N Lukáčová, M Maršala, J Maršala - Brain research bulletin, 2002 - Elsevier
root ganglia (DRGs) and dorsal horn of the corresponding spinal segments. NOS
catalytic activity was also determined by monitoring the conversion of [ 3 H ]arginine to [ 3 H ]citrulline …

[HTML][HTML] Melatonin suppresses neuropathic pain via MT2-dependent and-independent pathways in dorsal root ganglia neurons of mice

JJ Lin, Y Lin, TZ Zhao, CK Zhang, T Zhang, XL Chen… - Theranostics, 2017 - ncbi.nlm.nih.gov
… efficacy in treating different pain conditions. However, … in neuropathic pain (NP) are poorly
understood. To elucidate this process, pain behaviors were measured in a dorsal root ganglia (…

Downregulation of a dorsal root ganglion‐specifically enriched long noncoding RNA is required for neuropathic pain by negatively regulating RALY‐triggered Ehmt2 …

Z Pan, S Du, K Wang, X Guo, Q Mao, X Feng… - Advanced …, 2021 - Wiley Online Library
… Nerve injury-induced maladaptive changes of gene expression in dorsal root ganglion (DRG)
neurons contribute to neuropathic pain. Long non-coding RNAs (lncRNAs) are emerging …