… into the field of neuropathic pain. The fundamental aspects of neuropathic pain research
are introduced. Based on and guided along the anatomy of pain transmission, the established …

… of pain is challenging to implement Many drugs shown to be effective in preclinical models
of neuropathic pain … spontaneous, pain and do not account for the emotional aspects of pain …

… neuropathy, are reviewed. Although limited, data are consistent with the larger literature on
chronic pain and indicate that neuropathic pain … Depression and pain coping strategies such …

… for neuropathic pain. The International Association for the Study of Pain defines neuropathic
pain as pain … Some unique aspects of neuropathic pain include hyperalgesia (increased …

… neuropathic pain perception, treatment of mental decompensations such as depression and
anxiety and of recurrences, are critical to manage neuropathic pain … of neuropathic etiology. …

… from other therapeutic approaches. We thus review promising therapeutic targets that have
… We outline recent progress in understanding the etiology of neuropathic pain and show how …

… matrix) subserve the sensory, affective, cognitive, and attentional aspects of pain perception
and tune the individual pain.'13 The wide array of clinical presentations of neuropathic pain …

… BACKGROUND AND OBJECTIVES: Neuropathic pain is … biologic factors associated with
neuropathic pain, making a logical … the pathophysiology of neuropathic pain can determine new …

… neuropathic pain (first-line pharmacological treatment). Although they are very effective in
reducing pain in several neuropathic pain … first-line treatment for neuropathic pain. In addition …

… pain clinicians would accept that the current armamentarium of therapies for neuropathic pain
… understanding of the pathophysiology of neuropathic pain and inability to target treatments …