Neuropathic pain treatment: still a challenge

OJM Nascimento, BL Pessoa, M Orsini, P Ribeiro… - Neurology …, 2016 - mdpi.com
… to the diagnosis, although NP is still diagnosed based on clinical aspects.Initially, the
management of NP consists of drug therapy and interdisciplinary approaches. As the last resource, …

Challenges of neuropathic pain: focus on diabetic neuropathy

DC Rosenberger, V Blechschmidt… - Journal of Neural …, 2020 - Springer
therapeutic concepts. Our goal is to review current knowledge of the pathophysiology of
peripheral neuropathic pain, particularly painful diabetic neuropathy… of diabetic neuropathic pain

Overview of neuropathic pain syndromes

J Serra - Acta Neurologica Scandinavica, 1999 - Wiley Online Library
… Only when this has been achieved is it possible to plan adequate symptom‐oriented
therapeutic strategies. In the future, therapy will be more symptom‐oriented than illness‐oriented, …

Mechanisms of neuropathic pain

D Bridges, SWN Thompson… - British journal of …, 2001 - bjanaesthesia.org
therapeutics for neuropathic painpain, human volunteer models of neuropathic pain have
yet to be developed and animal models are, thus, the mainstay of such research and aspects

Neuropathic pain

E Kerstman, S Ahn, S Battu, S Tariq… - Handbook of clinical …, 2013 - Elsevier
… Central post-stroke pain (CPSP) is characterized by neuropathic pain in areas of the body
that have lost part of their sensory innervations due to the stroke. Published studies estimate …

Neuropathie pain-definition and implications for research and therapy

MM Backonja, CE Argoff - … Neuropathic Pain & Symptom Palliation, 2005 - Taylor & Francis
… advances related to neuropathic pain stem from the fact that neuropathic pain is the result of
… coping skills, and functional abilities and aspects related to quality of life, as outlined here: …

Experimental spinal cord stimulation and neuropathic pain: mechanism of action, technical aspects, and effectiveness

H Smits, M van Kleef, J Holsheimer… - Pain Practice, 2013 - Wiley Online Library
… of neuropathic pain. This article reviews the basic clinical and experimental technical aspects
… view of recent understanding of the dorsal horn pain circuit involved. These data may then …

Current challenges and future prospects in management of neuropathic pain

KK Jain - Expert review of Neurotherapeutics, 2008 - Taylor & Francis
… and clinical pharmacology of various diseases, but not for pain because the genetic
aspects of pain are just beginning to be unraveled. Genetic factors have been implicated in …

Role of neurotrophins in neuropathic pain

D Siniscalco, C Giordano, F Rossi… - Current …, 2011 - ingentaconnect.com
… significant roles in the development and transmission of neuropathic pain. Neuropathic pain
is initiated by a primary lesion or … Neuropathic pain ranks at the first place for sanitary costs. …

Ion channels and pain: Important steps towards validating a new therapeutic target for neuropathic pain

JS Trimmer - Experimental neurology, 2014 - Elsevier
… in an animal model of peripheral neuropathic pain. The authors were able to link this
downregulation to a crucial aspect of peripheral neuropathic pain, the hyperexcitability of the …