Potential biomarkers for persistent and neuropathic pain therapy

M Sisignano, J Lötsch, MJ Parnham… - … & therapeutics, 2019 - Elsevier
… in the optimal pharmacological treatment for individual pain patients. We highlight the
potential for biomarker-based individualized pain therapies and discuss biomarker reliability and …

Chronic neuropathic pain and its control by drugs

BV MacFarlane, A Wright, J O'Callaghan… - … & therapeutics, 1997 - Elsevier
aspects of the aetiology of five neurogenic painpain in the stump, as well as a painful
phantom limb. Upon consultation with a pain specialist, three distinct types of neuropathic pain

The kynurenine pathway as a potential target for neuropathic pain therapy design: from basic research to clinical perspectives

K Ciapała, J Mika, E Rojewska - International Journal of Molecular …, 2021 - mdpi.com
… Despite extensive research aimed at clarifying the mechanisms underlying the development
and maintenance of neuropathic pain, the roles of KP metabolites in this process are still not …

Chronic neuropathic pain: mechanisms, diagnosis, and treatment

RN Harden - The neurologist, 2005 - journals.lww.com
… -based approach to the treatment of neuropathic pain holds promise for improving the
quality of life of our patients with neuropathic pain. Chronic pain is not uncommon, although …

Pain and its treatments

P Cesaro, H Ollat - European neurology, 1997 - karger.com
… Models of neuropathic pain have advanced our understanding of its specific pathophysiology.
Sensoridiscriminative aspects of pain involve lateral thalamic nuclei and corresponding …

Central neuropathic pain

J Rosner, DC de Andrade, KD Davis… - Nature Reviews …, 2023 - nature.com
… system related to sensory-discriminative aspects of pain are displayed. The figure on the …
related to the sensory-discriminative aspects of central neuropathic pain (CNP). Dysfunction of …

Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential

K Inoue, M Tsuda - Nature Reviews Neuroscience, 2018 - nature.com
… It is also becoming clear that microglia have active roles in brain regions important for the
emotional and memory-related aspects of chronic pain. Recent advances in the development …

[HTML][HTML] Calcium channels as therapeutic targets in neuropathic pain

TL Yaksh - The Journal of Pain, 2006 - Elsevier
… be accompanied by concurrent changes in some aspect of motor function, but … pain behavior
and to serve as preclinical mechanistic predictors of drug target activity in neuropathic pain

Management of neuropathic pain associated with spinal cord injury

EM Hagen, T Rekand - Pain and therapy, 2015 - Springer
neuropathic pain as a result and shoulder pain due to muscular overuse [28, 29]. Peripheral
neuropathic painPain has profound impact on many aspects of daily life. The management …

[HTML][HTML] Neuropathic pain and chronic pain as an underestimated interdisciplinary problem

AK Szewczyk, A Jamroz-Wiśniewska… - International Journal …, 2022 - ncbi.nlm.nih.gov
… selected and assessed in several aspects, including the quality of life … , central neuropathic
pain and peripheral neuropathic pain are … estimate peripheral neuropathic pain, including the …