p38 mitogen-activated kinase (MAPK) is essential for equine neutrophil migration

RE Eckert, Y Sharief, SL Jones - Veterinary immunology and …, 2009 - Elsevier
… of p38 MAPK, MAPK-activated protein kinase 2 (MK2) (Hannigan et al., 2001). We hypothesized
that p38 MAPK is required for equine neutrophil migration in response to endogenous …

Neutrophil extracellular traps are downregulated by glucocorticosteroids in lungs in an equine model of asthma

A Vargas, R Boivin, P Cano, Y Murcia, I Bazin… - Respiratory …, 2017 - Springer
… We previously found that this cytokine induces the activation of equine neutrophils and
importantly, that it is not inhibited by GC [24]. However, IL-17’s contribution to NETs formation and …

Relationship between exercise-induced systemic inflammatory like reaction and racing performance in endurance horses

D Serteyn, I Caudron, JP Lejeune… - Comparative …, 2012 - wageningenacademic.com
… Despite the low numbers of horses in this study, muscle … , other specific markers of neutrophil
activation such as MPO and … Method for co-purification of equine neutrophil elastase and …

Genomic and non-genomic effects of dexamethasone on equine peripheral blood neutrophils

L Lecoq, P Vincent, A Lavoie-Lamoureux… - Veterinary immunology …, 2009 - Elsevier
… In the present study, we demonstrated that DEX is a fast and potent inhibitor of activated
equine peripheral blood neutrophils. These effects are mediated through both genomic and non-…

Plasma concentrations of myeloperoxidase in endurance and 3‐day event horses after a competition

T Art, T Franck, M Gangl, D Votion… - Equine Veterinary …, 2006 - Wiley Online Library
… hypothesised that neutrophil activation, … muscular pain (Pyne et al. 2000). Other authors
suggested that, in man, exercise results in neutrophil translocation to the active skeletal muscles

The effects of hyaluronic acid and exercise on equine skeletal muscle

SR Gregg - 2023 - vtechworks.lib.vt.edu
… expression of macrophage and neutrophil surface markers (… an anti-inflammatory in equine
skeletal muscle but does not … of muscle repair and regeneration, and when activated from …

Intravenous Injection of Sodium Hyaluronate Diminishes Basal Inflammatory Gene Expression in Equine Skeletal Muscle

SR Gregg, MR Barshick, SE Johnson - Animals, 2023 - mdpi.com
… an inflammatory environment within the muscle. Neutrophils within the muscle secrete TNFα
and IL1β … Genes involved in leukocyte activation and cytokine production are not irreversibly …

Myristoylated Alanine Rich C Kinase Substrate (MARCKS) is essential to β2-integrin dependent responses of equine neutrophils

MK Sheats, KC Pescosolido, EM Hefner… - Veterinary immunology …, 2014 - Elsevier
… on equine neutrophils in vitro, we demonstrate that inhibition of MARCKS function significantly
attenuates β2-integrin-dependent neutrophil … of IIC-mediated neutrophil activation. Both …

[HTML][HTML] Neutrophil extracellular traps and active myeloperoxidase concentrate in lamellar tissue of equids with naturally occurring laminitis

N Storms, G de la Rebière, T Franck… - Veterinary Immunology …, 2024 - Elsevier
… Laminitis is a pathology of the equine digit ultimately leading to a failure of the dermo-epidermal
interface. Neutrophil activation is recognized as a major factor in SIRS-associated …

Neutrophil and cytokine dysregulation in hyperinsulinemic obese horses

TC Holbrook, T Tipton, D McFarlane - Veterinary immunology and …, 2012 - Elsevier
… The positive correlation we detected between insulin concentration and neutrophil oxidative
burst activity indicates insulin may also be an important regulator of equine neutrophil