ICAM-1 and LFA-1 play critical roles in LPS-induced neutrophil recruitment into the alveolar space
A Basit, J Reutershan, MA Morris… - … of Physiology-Lung …, 2006 - journals.physiology.org
… ICAM-1 can contribute to the neutrophil recruitment. With the conclusive evidence for the role
of ICAM-1 in neutrophil recruitment … stage is set to dissect the level where ICAM-1 is critical. …
of ICAM-1 in neutrophil recruitment … stage is set to dissect the level where ICAM-1 is critical. …
Emerging mechanisms of neutrophil recruitment across endothelium
… the neutrophils that regulate various steps in the recruitment process. This review focuses
on these emerging pathways and the mechanisms that regulate neutrophil recruitment across …
on these emerging pathways and the mechanisms that regulate neutrophil recruitment across …
Intracellular signalling during neutrophil recruitment
… This analysis revealed that the initial steps of neutrophil polarization (within 1–5 min of
stimulation) occur at the leading edge of the cell, through Rac-mediated actin polymerization, …
stimulation) occur at the leading edge of the cell, through Rac-mediated actin polymerization, …
P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver
M Kamochi, F Kamochi, YB Kim… - … of Physiology-Lung …, 1999 - journals.physiology.org
… , increased after endotoxin in WT and P-selectin-deficient mice but not in P-selectin-ICAM-1 …
circulating neutrophils in endotoxin-treated ICAM-1-deficient mice and P-selectin-ICAM-1 …
circulating neutrophils in endotoxin-treated ICAM-1-deficient mice and P-selectin-ICAM-1 …
Induction of LFA-1-dependent neutrophil rolling on ICAM-1 by engagement of E-selectin
… Conclusion: The data show that neutrophil rolling on E-… LFA-1, enabling LFA-1-dependent
rolling on ICAM-1. This mechanism is likely to amplify and accelerate neutrophil recruitment in …
rolling on ICAM-1. This mechanism is likely to amplify and accelerate neutrophil recruitment in …
Role of ICAM-1 and ICAM-2 and alternate CD11/CD18 ligands in neutrophil transendothelial migration
AC Issekutz, D Rowter… - Journal of Leukocyte …, 1999 - academic.oup.com
… that ICAM-2 is a major contributor with ICAM-1 to LFA-1-mediated PMN transendothelial
migration. Furthermore, Mac-1… factors is ICAM-1 independent and only partly ICAM-1 dependent …
migration. Furthermore, Mac-1… factors is ICAM-1 independent and only partly ICAM-1 dependent …
[HTML][HTML] Transmigrated neutrophils in the intestinal lumen engage ICAM-1 to regulate the epithelial barrier and neutrophil recruitment
… ICAM-1 by PMN … ICAM-1 ligation on epithelial permeability and PMN migration in vivo were
blocked after intraluminal addition of peptides derived from the cytoplasmic domain of ICAM-1…
blocked after intraluminal addition of peptides derived from the cytoplasmic domain of ICAM-1…
Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1
C Strell, K Lang, B Niggemann, KS Zaenker… - Experimental cell …, 2010 - Elsevier
… ICAM-1 is coupled to intracellular signaling pathways involved in tumor cell migration. Thus,
neutrophil … act as modulators of the metastatic capability of tumor cells by ligation of ICAM-1. …
neutrophil … act as modulators of the metastatic capability of tumor cells by ligation of ICAM-1. …
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade
… It is also important to note that different chemokines, cytokines, and proinflammatory
molecules could recruit neutrophils via different adhesive mechanisms, and we cannot state that …
molecules could recruit neutrophils via different adhesive mechanisms, and we cannot state that …
Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow
AFH Lum, CE Green, GR Lee, DE Staunton… - Journal of Biological …, 2002 - ASBMB
… coated with ICAM-1. The strength and stability of neutrophil adhesion to an ICAM-1-…
neutrophil recruitment on ICAM-1 through changes in LFA-1 affinity and membrane mobility. …
neutrophil recruitment on ICAM-1 through changes in LFA-1 affinity and membrane mobility. …
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