Potential roles of neutrophils in regulating intestinal mucosal inflammation of inflammatory bowel disease

GX Zhou, ZJ Liu - Journal of digestive diseases, 2017 - Wiley Online Library
… macrophages is compromised, characterized by reduced production of TNF-α, leading to
decreased numbers of neutrophils recruited to the sites of inflammation and chronic intestinal …

Neutrophil recruitment, chemokine receptors, and resistance to mucosal infection

G Godaly, G Bergsten, L Hang, H Fischer… - Journal of leukocyte …, 2001 - academic.oup.com
… The two-step model for neutrophil recruitment and mucosal inflammation. Signal 1: bacterial
attachment to mucosal cells activates a first inflammatory response. The adhesin receptor …

[HTML][HTML] Macrophage–endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa

X Ren, LD Manzanares, EB Piccolo… - The Journal of …, 2023 - Am Soc Clin Investig
… in the number of VAMs in inflamed intestines. Our findings further implicated VAMs in a unique
crosstalk with inflamed ECs to promote PMN recruitment in inflamed mucosa. Specifically, …

Neutrophils and the inflammatory tissue microenvironment in the mucosa

EL Campbell, DJ Kao, SP Colgan - Immunological Reviews, 2016 - Wiley Online Library
… differences in the mechanisms of inflammation between various mucosal organs. Below, we
mucosal oxidases perform in a sequential fashion during inflammation, prior to recruitment

[HTML][HTML] The role of neutrophils during intestinal inflammation

BM Fournier, CA Parkos - Mucosal immunology, 2012 - Elsevier
… in the second enzymatic reaction as highlighted in Figure 3.88, 89, 90 Resolvin E1 and
protectin D1 both decrease neutrophil recruitment and enhance the phagocytosis of apoptotic …

Contributions of neutrophils to resolution of mucosal inflammation

SP Colgan, SF Ehrentraut, LE Glover, DJ Kominsky… - Immunologic …, 2013 - Springer
Neutrophil (polymorphonuclear leukocyte, PMN) recruitment and accumulation at sites of
tissue injury and infection has long been used as a biomarker of inflammation… that neutrophils

[HTML][HTML] Neutrophils as components of mucosal homeostasis

CHT Hall, EL Campbell, SP Colgan - Cellular and molecular …, 2017 - Elsevier
… mice had persistent IL17 production and neutrophil recruitment. The neutropenia associated
with … preparation to the inflamed mucosa could represent a novel therapeutic apprch for IBD. …

Mechanism of neutrophil recruitment induced by IL-8 in chronic sinusitis

H Suzuki, Y Takahashi, H Wataya, K Ikeda… - Journal of allergy and …, 1996 - Elsevier
… epithelial cells, attract neutrophils out of mucosa, and the neutrophils that have emigrated …
neutrophil recruitment is interrupted by the absence of the sinus effusion, and the inflammation

Blockade of poly (ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis

B Zingarelli, C Szabó, AL Salzman - Gastroenterology, 1999 - Elsevier
… To further elucidate the role of PARS on neutrophil accumulation in inflamed colon, we next
evaluated the intestinal expression of ICAM-1. Staining of colonic tissue sections obtained …

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

C Sina, O Gavrilova, M Förster, A Till… - The Journal of …, 2009 - journals.aai.org
… , which argues for accentuated role of Gpr43 for neutrophil recruitment in the gut mucosa. …
diet can induce recruitment of neutrophils and thus contribute to onset of inflammation. There …