Role of the NFκB-signaling pathway in cancer

L Xia, S Tan, Y Zhou, J Lin, H Wang… - OncoTargets and …, 2018 - Taylor & Francis
… , and VEGF, NFκB mediates tumor-cell proliferation, survival, and angiogenesis. Citation9
This … focuses on this NFκB-signaling pathway in tumors. Overview of NFκB-signaling pathways

Crosstalk in NF-κB signaling pathways

A Oeckinghaus, MS Hayden, S Ghosh - Nature immunology, 2011 - nature.com
signaling to other pathways. In this review we briefly introduce these important NF-κB signaling
… that allow for both integration and communication with non-NF-κB signaling pathways. …

Non-canonical NF-κB signaling pathway

SC Sun - Cell research, 2011 - nature.com
The non-canonical NF-κB pathway is an important arm of NF-κB signaling that predominantly
targets activation of the p52/RelB NF-κB complex. This pathway depends on the inducible …

NF-κB signaling pathway, inflammation and colorectal cancer

S Wang, Z Liu, L Wang, X Zhang - Cellular & molecular immunology, 2009 - nature.com
NF-κB has been shown to be activated in all cells, where it regulates expression of diverse
… last couple of years implicating NF-κB signaling pathways in carcinogneneisis of colorectal …

[HTML][HTML] NFκB-dependent signaling pathways

X Li, GR Stark - Experimental hematology, 2002 - Elsevier
… Once activated, TAK1 can directly phosphorylate IKKβ and MKK6, leading to the activation
of both the JNK and NFκB signaling pathways. TAK1 is also activated upon stimulation by …

[PDF][PDF] NF-κB signaling pathway and free radical impact

A Siomek - Acta Biochimica Polonica, 2012 - frontierspartnerships.org
… redox events regulate the NF-κB pathway is still unclear. … NF-κB signaling pathway.
Phosphorylation and dephosphorylation processes are crucial in the activation of preexisting NF-κB

Mutations in the NF-κB signaling pathway: implications for human disease

G Courtois, TD Gilmore - Oncogene, 2006 - nature.com
NF-κB signaling pathway have been implicated and discusses the molecular mechanisms by
which these alterations in NF-κB signaling … transducers of NF-κB signaling or disrupt NF-κB-…

Signaling to NF-κB

MS Hayden, S Ghosh - Genes & development, 2004 - genesdev.cshlp.org
pathway with the complexity of responses in which NF-κB family members play important
roles. In this review, we provide an overview of established NF-κB signaling pathwaysNF-κB

Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway

U Senftleben, Y Cao, G Xiao, FR Greten, G Krähn… - Science, 2001 - science.org
… In mammals, the canonical nuclear factor κB (NF-κB) signaling pathway activated in response
to infections is based on degradation of IκB inhibitors. This pathway depends on the IκB …

From calcium to NF-κB signaling pathways in neurons

A Lilienbaum, A Israël - Molecular and cellular biology, 2003 - Am Soc Microbiol
… the characterization of signaling pathways leading to the constitutive activation of NF-κB in …
intracellular stores is indispensable for the basal NF-κB activity. We demonstrated further that …