[HTML][HTML] NF-kappaB signaling in chronic inflammatory airway disease
M Schuliga - Biomolecules, 2015 - mdpi.com
… airway disease by augmenting NF-κB transrepression. This review examines NF-κB
signaling in airway inflammation and its potential as target for treatment of asthma and COPD. …
signaling in airway inflammation and its potential as target for treatment of asthma and COPD. …
A prominent role for airway epithelial NF-κB activation in lipopolysaccharide-induced airway inflammation
ME Poynter, CG Irvin… - The Journal of …, 2003 - journals.aai.org
… The objective of the present study was to address the causal role of airway epithelial NF-κB
activation in the initiation of airway inflammation in an experimental model of LPS inhalation. …
activation in the initiation of airway inflammation in an experimental model of LPS inhalation. …
Airway epithelium controls lung inflammation and injury through the NF-κB pathway
D Cheng, W Han, SM Chen, TP Sherrill… - The Journal of …, 2007 - journals.aai.org
… 2 or Escherichia coli LPS delivered directly to the airways or systemically via an osmotic pump
… the NF-κB pathway in airway epithelial cells is critical for generation of lung inflammation …
… the NF-κB pathway in airway epithelial cells is critical for generation of lung inflammation …
A critical role for NF-κB in GATA3 expression and TH2 differentiation in allergic airway inflammation
… 2 differentiation and allergic airway inflammation in vivo. Mice that lack the p50 subunit of
nuclear factor κB (NF-κB) are unable to mount airway eosinophilic inflammation. We show here …
nuclear factor κB (NF-κB) are unable to mount airway eosinophilic inflammation. We show here …
[HTML][HTML] Cigarette smoke induced airway inflammation is independent of NF-κB signalling
JMD Rastrick, CS Stevenson, S Eltom, M Grace… - PloS one, 2013 - journals.plos.org
… We showed in an airway inflammation model known to be NF-κB-dependent that the NF-κB …
Then, using the same methods, we demonstrated that the NF-κB pathway appears not to …
Then, using the same methods, we demonstrated that the NF-κB pathway appears not to …
Curcumin attenuates allergic airway inflammation and hyper-responsiveness in mice through NF-κB inhibition
SW Oh, JY Cha, JE Jung, BC Chang, HJ Kwon… - Journal of …, 2011 - Elsevier
… In sensitized guinea pigs, curcumin was shown to attenuate OVA-induced AHR, although
the effect of curcumin on the airway inflammatory response was not reported in this study (Ram …
the effect of curcumin on the airway inflammatory response was not reported in this study (Ram …
Curcumin attenuates airway inflammation and airway remolding by inhibiting NF-κB signaling and COX-2 in cigarette smoke-induced COPD mice
J Yuan, R Liu, Y Ma, Z Zhang, Z Xie - Inflammation, 2018 - Springer
… We conclude that curcumin alleviates airway inflammation and airway remolding in LC-challenged
mice and suppresses LC-induced NF-κB and COX-2 expression both in vivo and in …
mice and suppresses LC-induced NF-κB and COX-2 expression both in vivo and in …
Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-κB activity in a murine model of asthma
Y Shi, J Dai, H Liu, RR Li, PL Sun, Q Du… - Canadian journal of …, 2009 - cdnsciencepub.com
… attenuate allergen-induced airway inflammation and its possible … the development of airway
inflammation and airway reactivity. … We also tested NF-κB binding activity by electrophoretic …
inflammation and airway reactivity. … We also tested NF-κB binding activity by electrophoretic …
NF-κB activation in airways modulates allergic inflammation but not hyperresponsiveness
ME Poynter, R Cloots, T van Woerkom… - The Journal of …, 2004 - journals.aai.org
… epithelium in animal models of allergic airway inflammation (6, 7) and in patients … airway
epithelial NF-κB-driven inflammation and other immune alterations are uncoupled from airways …
epithelial NF-κB-driven inflammation and other immune alterations are uncoupled from airways …
[HTML][HTML] NF-κB: a key role in inflammatory diseases
PP Tak, GS Firestein - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-κB activity
… IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. …
… IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. …
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