Inhibition of NF-κB improves left ventricular remodeling and cardiac dysfunction after myocardial infarction

Y Onai, J Suzuki, Y Maejima… - American Journal …, 2007 - journals.physiology.org
… In conclusion, inhibition of NF-κB activation may reduce the … approach to prevent adverse
cardiac remodeling after MI. … This adverse LV remodeling causes depressed cardiac

Interaction between NFκB and NFAT coordinates cardiac hypertrophy and pathological remodeling

Q Liu, Y Chen, M Auger-Messier… - Circulation research, 2012 - Am Heart Assoc
… No NFκB binding sites have been identified in the promoter … fetal cardiac genes associated
with cardiac hypertrophy. We showed that NFκB affected cardiac hypertrophy and remodeling

[HTML][HTML] Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction

A Han, Y Lu, Q Zheng, J Zhang, YZ Zhao… - Cellular Physiology and …, 2018 - karger.com
κB (NF-κB) is increasingly recognized as a crucial player in the development of cardiac
remodeling … A member of the NF-κB family, p65, forms homo or heterodimers that are bound to …

IL-33 attenuates cardiac remodeling following myocardial infarction via inhibition of the p38 MAPK and NF-κB pathways Retraction in/10.3892/mmr. 2022.12868

H Yin, P Li, F Hu, Y Wang… - Molecular Medicine …, 2014 - spandidos-publications.com
… demonstrated that p38 mitogen-activated protein kinase (p38 MAPK) and nuclear factor-κB
(NF-κB) activation are involved in myocardial damage and adverse cardiac remodeling (8,9). …

Increased JNK, AP-1 and NF-κB DNA binding activities in isoproterenol-induced cardiac remodeling

Y Takemoto, M Yoshiyama, K Takeuchi… - Journal of molecular and …, 1999 - Elsevier
cardiac remodeling may be in part mediated by JNK ac- thermore, NF-B activation in
isoproterenol-induced cardiac remodeling … Our in vivo observations suggest that NF-B and JNK …

Targeted deletion of nuclear factor κB p50 enhances cardiac remodeling and dysfunction following myocardial infarction

L Timmers, JK van Keulen, IE Hoefer… - Circulation …, 2009 - Am Heart Assoc
… was increased in NF-κB p50 knockout … NF-κB p50 results in enhanced cardiac remodeling
and functional deterioration following myocardial infarction by increasing matrix remodeling

Inhibition of Dectin-1 in mice ameliorates cardiac remodeling by suppressing NF-κB/NLRP3 signaling after myocardial infarction

X Li, Y Bian, P Pang, S Yu, X Wang, Y Gao, K Liu… - International …, 2020 - Elsevier
… infarction (MI), which may deteriorate cardiac remodeling and lead to dysfunction in the heart
post-… of Dectin-1 on cardiac remodeling post-MI. We found that cardiac Dectin-1 mRNA and …

Curcumol alleviates cardiac remodeling via the AKT/NF-κB pathway

Z Fang, S Li, F Yushanjiang, G Feng, S Cui… - International …, 2023 - Elsevier
… Currently, only a limited number of specific drugs are available for the treatment of cardiac
remodeling. Further research into the molecular mechanism underlying cardiac remodeling

Aldosterone target NGAL (neutrophil gelatinase–associated lipocalin) is involved in cardiac remodeling after myocardial infarction through NFκB pathway

E Martínez-Martínez, M Buonafine, I Boukhalfa… - …, 2017 - Am Heart Assoc
… The purpose of this study was to investigate the role of the recently identified MR target
NGAL in cardiac remodeling and function after MI. Serum NGAL was associated with less LVEF …

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling

L Schirone, M Forte, S Palmerio, D Yee… - Oxidative medicine …, 2017 - Wiley Online Library
cardiac remodeling that, when prolonged, leads to heart failure progression. Here, we review
the molecular pathways involved in cardiac remodeling… involved in cardiac remodeling may …