… suggest this pathway may prove a difficult target in the treatment of chronic disease. In this
article, we discuss the role of NF-κB in inflammation in light of these recent studies. NF-κB has …

… This study confirmed that NF-κB-induced inflammation is directly linked to growth stimulation
of malignant cells. A further mechanism whereby NF-κB might be involved is through …

… activation of this pathway contributes to the … NF-κB pathway. We also discuss recent
progress in elucidating the molecular mechanisms regulating non-canonical NF-κB pathway …

… NF-κB pathway, the potential for inhibiting this pathway has received attention. Agents that
inhibit this pathway… with activation of the NF-κB pathway and consider therapeutic strategies to …

… roles for NF-κB that may have important implications for targeting this pathway in the treatment
… In this review we will discuss the emerging role of NF-κB in the resolution of inflammation …

… In contrast to the canonical NF-κB pathway, the noncanonical NF-κB pathway selectively
responds to a specific group of stimuli, including ligands of a subset of TNFR superfamily …

… cells lack the NF-κB/Rel signaling pathway show that NF-κB plays a … NF-κB activation increases
expression of the adhesion … of NF-κB as a key player in the pathogenesis of inflammation …

… pathways, providing a mechanism for the cells in response to a wide variety of stimuli linking
to inflammation. … canonical but also non-canonical NF-κB pathways. To initiate both of these …

… activate NF-κB through the classical pathway in somatic renal cells, and noncanonical
pathway … Under most test conditions, specific NF-κB inhibitors tend to reduce inflammation in …

… inflammation by suppressing NF-κB in animal models. Drugs targeting NF-κB have been found
to not only suppress inflammation … joint inflammation by inhibiting the NF-κB pathway and …