Active repression of antiapoptotic gene expression by RelA (p65) NF-κB
KJ Campbell, S Rocha, ND Perkins - Molecular cell, 2004 - cell.com
… Here, we demonstrate that NF-κB induced by cytotoxic stimuli, such as ultraviolet light (UV-C…
RelA(p65) NF-κB subunit. Furthermore, UV-C and daunorubicin inhibit TNF-induced NF-κB …
RelA(p65) NF-κB subunit. Furthermore, UV-C and daunorubicin inhibit TNF-induced NF-κB …
A new member of the IκB protein family, IκBε, inhibits RelA (p65)-mediated NF-κB transcription
Z Li, GJ Nabel - Molecular and cellular biology, 1997 - Am Soc Microbiol
… IκBε interacts with different NF-κB proteins, including p65 (RelA), c-Rel, p50, and p52, in …
both p50-p65 and p50–c-Rel complexes effectively. Endogenous and transfected NF-κB (RelA-…
both p50-p65 and p50–c-Rel complexes effectively. Endogenous and transfected NF-κB (RelA-…
Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6.
C Kunsch, RK Lang, CA Rosen… - Journal of immunology …, 1994 - journals.aai.org
… Although we have previously demonstrated that the RelA subunit of NF-KB can bind to the
NF-KB binding element (E), the binding of C/EBP/NF-IL-6 family members to this region of the …
NF-KB binding element (E), the binding of C/EBP/NF-IL-6 family members to this region of the …
Inhibition of interleukin-1-stimulated NF-κB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity
LJ Egan, DC Mays, CJ Huntoon, MP Bell… - Journal of Biological …, 1999 - ASBMB
… Many of the stimuli that activate NF-κB by inducing IκB degradation also cause phosphorylation
of the NF-κB RelA (p65) polypeptide. The transactivating capacity of RelA is positively …
of the NF-κB RelA (p65) polypeptide. The transactivating capacity of RelA is positively …
RelA/p65 is a molecular target for the immunosuppressive action of protein kinase A.
M Neumann, T Grieshammer, S Chuvpilo… - The EMBO …, 1995 - embopress.org
… IKB, no increase in synthesis of p65/RelA was observed. The … of p65, while DNA binding of
c-Rel was stimulated following PKA activation. Since suppressed nuclear translocation of p65 …
c-Rel was stimulated following PKA activation. Since suppressed nuclear translocation of p65 …
Nuclear factor-κB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue
N Sasaki, T Morisaki, K Hashizume, T Yao… - Clinical Cancer …, 2001 - AACR
… We primarily used immunohistochemistry to detect NF-κB … human RelA (p65) that binds not
only the active form of RelA … inactive form) RelA separately to evaluate NF-κB activation (Fig…
only the active form of RelA … inactive form) RelA separately to evaluate NF-κB activation (Fig…
[HTML][HTML] Nuclear factor-kB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue
LL Yu, HG Yu, JP Yu, HS Luo, XM Xu… - World journal of …, 2004 - ncbi.nlm.nih.gov
… RelA/NF-κB pathway is activated constitutively in colorectal carcinoma tissues, suggesting
that activation of RelA/NF-κB … of NF-κB activation and to determine whether NF-κB might serve …
that activation of RelA/NF-κB … of NF-κB activation and to determine whether NF-κB might serve …
NF-κB p65 (RelA) homodimer uses distinct mechanisms to recognize DNA targets
YQ Chen, LL Sengchanthalangsy, A Hackett, G Ghosh - Structure, 2000 - cell.com
… the mechanism of κB DNA recognition by the p65 homodimer, we have determined the
crystal structures of two new p65–DNA complexes. One contains the pseudosymmetric κB DNA …
crystal structures of two new p65–DNA complexes. One contains the pseudosymmetric κB DNA …
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor κB in tumor necrosis factor-related apoptosis-inducing ligand signaling
X Chen, K Kandasamy, RK Srivastava - Cancer research, 2003 - AACR
… Because RelA (p65) subunit of NF-κB enhanced NF-κB-DNA binding … of NF-κB. MDA-MB-231
cells were transiently transfected with plasmid cDNAs containing various subunits of NF-κB …
cells were transiently transfected with plasmid cDNAs containing various subunits of NF-κB …
RelA/p65 regulation of IκBβ
E Hertlein, J Wang, KJ Ladner, N Bakkar… - … and cellular biology, 2005 - Taylor & Francis
… and IκBα, much less is known regarding the regulation of IκBβ by NF-κB. Here, we describe
in detail the regulation of IκBβ by RelA/p65. Using p65 −/− fibroblasts, we show that IκBβ is …
in detail the regulation of IκBβ by RelA/p65. Using p65 −/− fibroblasts, we show that IκBβ is …
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