NF-κB RelA phosphorylation regulates RelA acetylation

LF Chen, SA Williams, Y Mu, H Nakano… - … and cellular biology, 2005 - Taylor & Francis
… that both phosphorylation and acetylation of RelA are required for NF-κB to achieve its full
… The different posttranslational modifications of the RelA subunit of NF-κB at specific sites …

The Serine Phosphatase SerB of Porphyromonas gingivalis Suppresses IL-8 Production by Dephosphorylation of NF-κB RelA/p65

H Takeuchi, T Hirano, SE Whitmore, I Morisaki… - PLoS …, 2013 - journals.plos.org
NF-κB is a transcriptional regulator that controls important aspects of innate immune … , and
NF-κB RelA/p65 homodimers regulate transcription of IL8. Phosphorylation of the NF-κB p65

Rho-kinase regulation of TNF-α-induced nuclear translocation of NF-κB RelA/p65 and M-CSF expression via p38 MAPK in mesangial cells

K Matoba, D Kawanami, M Tsukamoto… - American Journal …, 2014 - journals.physiology.org
… of NF-κB RelA/p65 and subsequent DNA binding activity, with no significant effects on IκBα
degradation and RelA/p65 … for the nuclear uptake of RelA/p65. Collectively, these findings …

Rel/NF-κB and IκB proteins: an overview

MJ May, S Ghosh - Seminars in cancer biology, 1997 - Elsevier
… Purification of NF-κB was performed using κB site-specific DNA affinity … NF-κB1) and p65
(RelA), were subsequently shown to form heterodimers that bound specifically to the cognate κB

New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor

JW Kim, SM Jang, CH Kim, JH An, EJ Kang… - Journal of Biological …, 2012 - ASBMB
… of NF-κB RelA/p65 and enhances RelA/p65RelA/p65 on the NF-κB target gene promoters
with the goal of determining the critical association time point in the TNF-α-induced NF-κB

p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB

RF Johnson, II Witzel, ND Perkins - Cancer research, 2011 - AACR
… In this study, we define a function of NF-κB in regulation of cellular respiration that is … which
RelA can regulate mitochondrial function, with important implications for how NF-κB activity …

Dimerization of NF-KB2 with RelA (p65) regulates DNA binding, transcriptional activation, and inhibition by an IκB-α (MAD-3)

CS Duckett, ND Perkins, TF Kowalik… - … and cellular biology, 1993 - Taylor & Francis
… /p65 heterodimers to both the HIV KB site and the related H-2 site (5, 18) are determined,
and the ability of NFKB2(p49)/RelA(p65) … We show that heterodimeric NFKB2(p49)/RelA(p65) …

Involvement of the p65/RelA subunit of NF-κB in TNF-α-induced SIRT1 expression in vascular smooth muscle cells

HN Zhang, L Li, P Gao, HZ Chen, R Zhang… - Biochemical and …, 2010 - Elsevier
… chromatin immunoprecipitation assays, we found that p65/RelA bound to the SIRT1 promoter
at a consensus NF-κB binding site. Our study indicates that p65/RelA mediates the TNF-α-…

Nuclear factor (NF)-κB proteins: therapeutic targets

IM Verma - Annals of the rheumatic diseases, 2004 - ard.bmj.com
NF-κB family has multiple members including RelA (p65), NF-… All members of the NF-κB
family except RelB can form … form of NF-κB is the heterodimer of subunit p65 associated with …

The p65/RelA subunit of NF-κB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor

JY Reuther-Madrid, D Kashatus, S Chen… - … and cellular biology, 2002 - Taylor & Francis
… the p65/RelA subunit of NF-κB as well as in cells expressing the super-repressor form of IκB.
In addition, the data indicate that the ability of p65/RelA to … Since NF-κB has previously been …