NF-κB activation as a pathological mechanism of septic shock and inflammation
SF Liu, AB Malik - … Journal of Physiology-Lung Cellular and …, 2006 - journals.physiology.org
… In this review, we will summarize the current research on NF-κB and its … and septic shock.
We will review the current knowledge about the role of NF-κB and NF-κB pathways in septic …
We will review the current knowledge about the role of NF-κB and NF-κB pathways in septic …
A pivotal role of endothelial-specific NF-κB signaling in the pathogenesis of septic shock and septic vascular dysfunction
J Ding, D Song, X Ye, SF Liu - The Journal of Immunology, 2009 - journals.aai.org
… to septic vascular dysfunction. Our data define the mechanistic role of endothelial-intrinsic
NF-κB in the pathogenesis of septic shock and septic … mechanisms of sepsis and septic shock. …
NF-κB in the pathogenesis of septic shock and septic … mechanisms of sepsis and septic shock. …
[PDF][PDF] Cellular activation mechanisms in septic shock
JS Downey, J Han - Front Biosci, 1998 - article.imrpress.com
… septic shock (8). Moreover, almost all genes central to the pathogenesis of septic shock contain
promoter elements for NF-κB, … of I-κB, prior to its degradation and NFκB activation (82,83,…
promoter elements for NF-κB, … of I-κB, prior to its degradation and NFκB activation (82,83,…
Erastin inhibits septic shock and inflammatory gene expression via suppression of the NF-κB pathway
BM Oh, SJ Lee, GL Park, YS Hwang, J Lim… - Journal of clinical …, 2019 - mdpi.com
… during sepsis remains unknown. Here, we showed that erastin ameliorates septic shock …
-light-chain-enhancer of activated B cells (NF-κB) in LPS-stimulated BMDMs. Our findings …
-light-chain-enhancer of activated B cells (NF-κB) in LPS-stimulated BMDMs. Our findings …
A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock
… septic shock patients. We genotyped 59 SNPs in the NF-κB pathway in a discovery cohort of
septic shock … rs7222094 T/C within MAP3K14 (NF-κB inducing kinase; NIK) associated with …
septic shock … rs7222094 T/C within MAP3K14 (NF-κB inducing kinase; NIK) associated with …
Critical advances in septicemia and septic shock
UN Das - Critical care, 2000 - Springer
… to develop and also recover from sepsis and septic shock. This suggests that it may be
possible to predict the development of septicemia and septic shock in a given individual and take …
possible to predict the development of septicemia and septic shock in a given individual and take …
TNFAIP2 inhibits early TNFa-induced NF-κB signaling and decreases survival in septic shock patients
… septic shock patients in the St. Paul’s Hospital Intensive Care Unit. We found that TNFAIP2
inhibits NFκB … in a cohort of septic shock patients in the Vasopressin and Septic Shock Trial (…
inhibits NFκB … in a cohort of septic shock patients in the Vasopressin and Septic Shock Trial (…
In vivo inhibition of nuclear factor-kappa B activation prevents inducible nitric oxide synthase expression and systemic hypotension in a rat model of septic shock.
SF Liu, X Ye, AB Malik - Journal of immunology (Baltimore, Md …, 1997 - journals.aai.org
… PDTC also prevented the expression of several other NF-KB-dependent genes in vitro (2327…
NF-KB activation in a rat model of septic shock and determined the in vivo function of NF-KB …
NF-KB activation in a rat model of septic shock and determined the in vivo function of NF-KB …
Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-κB and induces apoptosis in human cardiac myocytes
A Kumar, A Kumar, P Michael, D Brabant… - Journal of Biological …, 2005 - ASBMB
… septic shock … Septic shock is a serious disorder with significant morbidity and mortality
despite appropriate antibiotic and supportive therapy. Ultimately, patients with fatal septic shock …
despite appropriate antibiotic and supportive therapy. Ultimately, patients with fatal septic shock …
Septic shock
D Annane, E Bellissant, JM Cavaillon - The Lancet, 2005 - thelancet.com
… Septic shock is sepsis with hypotension that persists after resuscitation with intravenous
fluid. … inflammation occurs, converting the infection to sepsis, severe sepsis, or septic shock. …
fluid. … inflammation occurs, converting the infection to sepsis, severe sepsis, or septic shock. …
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