… In this review, we will summarize the current research on NF-κB and its … and septic shock.
We will review the current knowledge about the role of NF-κB and NF-κB pathways in septic …

… to septic vascular dysfunction. Our data define the mechanistic role of endothelial-intrinsic
NF-κB in the pathogenesis of septic shock and septic … mechanisms of sepsis and septic shock. …

… septic shock (8). Moreover, almost all genes central to the pathogenesis of septic shock contain
promoter elements for NF-κB, … of I-κB, prior to its degradation and NFκB activation (82,83,…

… during sepsis remains unknown. Here, we showed that erastin ameliorates septic shock …
-light-chain-enhancer of activated B cells (NF-κB) in LPS-stimulated BMDMs. Our findings …

… septic shock patients. We genotyped 59 SNPs in the NF-κB pathway in a discovery cohort of
septic shock … rs7222094 T/C within MAP3K14 (NF-κB inducing kinase; NIK) associated with …

… to develop and also recover from sepsis and septic shock. This suggests that it may be
possible to predict the development of septicemia and septic shock in a given individual and take …

… septic shock patients in the St. Paul’s Hospital Intensive Care Unit. We found that TNFAIP2
inhibits NFκB … in a cohort of septic shock patients in the Vasopressin and Septic Shock Trial (…

… PDTC also prevented the expression of several other NF-KB-dependent genes in vitro (2327…
NF-KB activation in a rat model of septic shock and determined the in vivo function of NF-KB …

… septic shock … Septic shock is a serious disorder with significant morbidity and mortality
despite appropriate antibiotic and supportive therapy. Ultimately, patients with fatal septic shock …

… Septic shock is sepsis with hypotension that persists after resuscitation with intravenous
fluid. … inflammation occurs, converting the infection to sepsis, severe sepsis, or septic shock. …