… Our extensive knowledge of Rel/NF-κB signaling betrays also our profound ignorance.
We … and signaling conditions, it is still not known what is the contribution of specific Rel/NF-κB …

… for NF-κB-responsive gene’s regulation where NF-κB … for NF-κB. Thus, the current review
will focus on these recent progresses that have been made on NF-κB signaling transduction …

… The inducible transcription factor NF-κB plays a central role in … the signaling mechanisms
that control the activation of NF-κB … forward in understanding this important signaling pathway. …

… Conversely, RNAi-mediated knockdown of TRAF7 expression inhibited the activation of
NF-κB in response to stimulation with TNF-α (Fig. 3c). To delineate the signal transduction …

… nuclear signal transduction pathway. We provide evidence that NF-icB is unlikely to mediate
the previously described UPR pathway. Hence, NF-KB mediates a novel signal transduction …

… The Rel/NF-κB signal transduction pathway is misregulated … Constitutive activation of the
Rel/NF-κB pathway can contribute … In many cases, inhibition of Rel/NF-κB activity reverses all or …

… here show that overall NF-acB signal transduction begins with a parallel … signal NF-udl
activation.We dguish thesimulispecific pathways by showing that the oxidative stimuli trigger NF-…

… of the Rel/NF-κB signal transduction pathway. Various extracellular signals can initiate a …
and degradation of IκB, which allows NF-κB to enter the nucleus and regulate specific gene …

… pathway by IFN, and the activation of NF-κB pathway by viruses, lipopolysaccharides, and
… the activation of NF-κB signal pathway by IFN and the role that NF-κB plays in modulating …

… degradation and the release of NF-κB for nuclear translocation and activation of … NF-κB
activation pathways, including the TRAF (TNF receptor–associated factor) proteins, IKK, NF-κB, …