… In arthritic tissues, the NF-κB signaling pathway can be … Overall, NF-κB signaling affects
cartilage matrix remodeling, … Interaction between redox signaling and NF-κB transcription …

Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation, and
aging. Mechanical stress along with synovial inflammation promotes the degradation of the …

… to osteoarthritis (OA) onset and progression. Therefore, targeted strategies that interfere with
NF-κB … In this review, we discuss the involvement of NF-κB in OA pathogenesis and how …

… that pro-inflammatory cytokine stimulate the NF-κB signaling pathway via binding to
corresponding receptor subunits, provoking a signaling cascade that leads to p65 phosphorylation …

… NF-κB signaling … NF-κB signaling pathway, which induces destruction of the articular joint,
leading to OA onset and progression. In this review, we discuss the involvement of NF-κB in …

… Mechanically, NF-κB can act as a transcriptional factor to regulate the expression of pro-…
Thus, NF-κB signaling has become a potential target, and inhibition of NF-κB signaling can …

… This review focuses on the NF-κB signaling pathways, emphasizing their role in inflammation
and damage to articular tissues and their modulation with therapeutic agents currently in …

… in osteoarthritis is critically reviewed. The organisation of the core signal transduction …
It is important to bear in mind that osteoarthritis is probably not a single disease entity: it is …

Osteoarthritis (OA) is a common chronic degenerative disease characterized by … Moreover,
suppression of the Akt signaling pathway and activation of NF‐κB signaling in chondrocytes …

… and disclose whether the inhibition of NF-κB signaling can induce ACSCs activation thus …
the NF-κB pathway and potently impair the responsiveness of ACSCs, whereas the NF-κB …