NF-κB signaling pathways: role in nervous system physiology and pathology

S Mincheva-Tasheva, RM Soler - The Neuroscientist, 2013 - journals.sagepub.com
signaling molecules such as neurotrophic factors or calcium. These molecules activate
intracellular signaling pathways… the important role of NF-κB signaling pathway in the regulation of …

NF-κB signaling pathway and its therapeutic implications in human diseases

FH Sarkar, Y Li, Z Wang, D Kong - International reviews of …, 2008 - Taylor & Francis
… have shown that NF-κB signaling also plays critical roles in the epithelial-mesenchymal
transition (EMT) and cancer stem cells. Therefore, targeting of NF-κB signaling pathway could be …

Crosstalk in NF-κB signaling pathways

A Oeckinghaus, MS Hayden, S Ghosh - Nature immunology, 2011 - nature.com
signaling to other pathways. In this review we briefly introduce these important NF-κB signaling
… that allow for both integration and communication with non-NF-κB signaling pathways. …

Mutations in the NF-κB signaling pathway: implications for human disease

G Courtois, TD Gilmore - Oncogene, 2006 - nature.com
NF-κB signaling pathway have been implicated and discusses the molecular mechanisms by
which these alterations in NF-κB signaling … transducers of NF-κB signaling or disrupt NF-κB-…

NF-κB signaling pathway, inflammation and colorectal cancer

S Wang, Z Liu, L Wang, X Zhang - Cellular & molecular immunology, 2009 - nature.com
… This review will focus on new data that have emerged over the last couple of years implicating
NF-κB signaling pathways in carcinogneneisis of colorectal cancer (CRC), the one of the …

NF-kappaB signaling pathways in neurological inflammation: a mini review

RH Shih, CY Wang, CM Yang - Frontiers in molecular neuroscience, 2015 - frontiersin.org
… All of these target proteins syntheses are mediated through NF-κB-dependent signaling
pathway. NF-κB has been shown to activate more than 500 genes, which are implicated in …

The Rel/NF-κB signal transduction pathway: introduction

TD Gilmore - Oncogene, 1999 - nature.com
… A pathway similar to the Rel/NF-κB signaling pathway … /NF-κB signaling betrays also our
profound ignorance. We still have very little appreciation for the in vivo dynamics of this pathway. …

From calcium to NF-κB signaling pathways in neurons

A Lilienbaum, A Israël - Molecular and cellular biology, 2003 - Am Soc Microbiol
… We report here the characterization of signaling pathways leading to the constitutive
activation of NF-κB in primary cultures of neonatal cerebellar granule neurons, consecutive to …

NF-κB signaling pathways in mammalian and insect innate immunity

N Silverman, T Maniatis - Genes & development, 2001 - genesdev.cshlp.org
… This study also sheds light on the role of the MAP3 kinase NIK in the NF-κB signaling
pathway. Relatively little p52 is produced in most cell types, even though p100 is present, so it …

Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer

A Soleimani, F Rahmani, GA Ferns, M Ryzhikov… - Gene, 2020 - Elsevier
… Over-activation of the NF-κB pathway is a feature of colorectal … Suppression of the NF-κB
signaling pathway using biological or … the regulatory role of NF-κB signaling pathway in the …