Sophora flavescens Aiton inhibits the production of pro-inflammatory cytokines through inhibition of the NF κB/IκB signal pathway in human mast cell line (HMC-1)

MH Hong, JY Lee, H Jung, DH Jin, HY Go, JH Kim… - Toxicology in vitro, 2009 - Elsevier
… Preparation of Sophora flavescens Aiton (SFA) extract Sophora flavescens Aiton (SFA)
used in this study was purchased from Omniherb (Gyeong Buk, Korea). The dried roots of SFA (…

A novel type lavandulyl flavonoid from Sophora flavescens as potential anti-hepatic injury agent that inhibit TLR2/NF-κB signaling pathway

Y Lin, XJ Chen, JJ Li, L He, YR Yang, F Zhong… - Journal of …, 2023 - Elsevier
… Ku Shen, derived from the roots of Sophora flavescens Aiton (Fabaceae), is one of popular
herbal medicines. Plant name was Sophora flavescens Aiton confirmed on October 27, 2022 …

Sophora flavescens-Angelica sinensis in the treatment of eczema by inhibiting TLR4/MyD88/NF-κB pathway

P Sun, X Zhao, W Zhao, L Chen, X Liu, Z Zhan… - Journal of …, 2024 - Elsevier
… of Sophora flavescens-Angelica sinensis (SA) in the treatment and control of eczema. …
The formula consists of four taels of pure Sophora flavescens and two taels of pure Angelica …

Pseudomonas aeruginosa-induced IL-1β production is inhibited by Sophora flavescens via the NF-κB/inflammasome pathways

JH Lee, H Shin, YJ Kim, SH Paek, S Jin, UH Ha - Journal of Microbiology, 2014 - Springer
Sophora flavescens is a traditional herbal medicine used to reduce inflammation, but no
study has examined its ability to block IL-1β production. Here, we show that S. …

Sophoraflavanone M, a prenylated flavonoid from Sophora flavescens Ait., suppresses pro-inflammatory mediators through both NF-κB and JNK/AP-1 signaling …

Y Han, X Zhang, Y Kang, Y Gao, X Li, R Qi… - European Journal of …, 2021 - Elsevier
… the anti-inflammatory herb Sophora flavescens Ait. We firstly … of prenylated flavonoids from
Sophora flavescens Ait., that of … inflammatory signaling pathways, NF-κB and JNK/AP-1. SFM …

Anti-inflammatory effect of sophoraflavanone G isolated from Sophora flavescens in lipopolysaccharide-stimulated mouse macrophages

ZY Wun, CF Lin, WC Huang, YL Huang, PY Xu… - Food and chemical …, 2013 - Elsevier
… Sophoraflavanone G (SG; 5,7,D, 2′,4′-tetrahydroxy-8-lavandulylflavanone) has been
isolated from Sophora flavescens and found to be effective against bacteria and to decrease …

Lavandulyl flavonoids from Sophora flavescens suppress lipopolysaccharide-induced activation of nuclear factor-κB and mitogen-activated protein kinases in …

JM Han, YY Jin, HY Kim, KH Park, WS Lee… - Biological and …, 2010 - jstage.jst.go.jp
… Previously, we examined LDL-antioxidant activities of the nine flavonoids isolated from
Sophora flavescens. Among these, two lavandulyl flavonoids, kurarinone (1) and kuraridin (2) in…

Anti‐Inflammatory and PPAR Transactivational Properties of Flavonoids from the Roots of Sophora flavescens

TH Quang, NTT Ngan, CV Minh, PV Kiem… - Phytotherapy …, 2013 - Wiley Online Library
… the roots of Sophora flavescens were evaluated using NF-κB-… Compounds 4 and 8 significantly
inhibited TNFα-induced NF-κBflavescens and warrant further studies to develop new …

Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study

C Han, H Wei, J Guo - BMC complementary and alternative medicine, 2011 - Springer
… Of the huge array of candidates available, we chose to investigate Sophora flavescens (Leguminosae)
because of its potential health promoting properties; it is anti-inflammatory, an anti…

Anti-Inflammatory and Antiproliferative Activities of Trifolirhizin, a Flavonoid from Sophora flavescens Roots

H Zhou, H Lutterodt, Z Cheng, L Yu - Journal of agricultural and …, 2009 - ACS Publications
… Trifolirhizin, a pterocarpan flavonoid, was isolated from the roots of Sophora flavescens,
and its chemical structure was confirmed by 1 H and 13 C NMR and MS spectra. Its anti-…