Toxicological evaluation of aerosols of a tobacco extract formulation and nicotine formulation in acute and short-term inhalation studies
MS Werley, AM Jerome, MJ Oldham - Inhalation Toxicology, 2014 - Taylor & Francis
… and a laboratory prepared nicotine formulation. We conducted comparative toxicological
evaluations using the inhalation exposure route for both formulation types across the same …
evaluations using the inhalation exposure route for both formulation types across the same …
Toxicological assessment of a prototype e-cigaret device and three flavor formulations: a 90-day inhalation study in rats
MS Werley, DJ Kirkpatrick, MJ Oldham… - … Toxicology, 2016 - Taylor & Francis
… and three formulations, we conducted an inhalation exposure study using rats to evaluate
the potential biological impact of vehicle, nicotine and a commercial flavor formulation at …
the potential biological impact of vehicle, nicotine and a commercial flavor formulation at …
[HTML][HTML] Application of ToxTracker for the toxicological assessment of tobacco and nicotine delivery products
DE Smart, S Bozhilova, F Miazzi, LE Haswell… - Toxicology Letters, 2022 - Elsevier
… range of nicotine delivery … ), tobacco heating product (THP 1.4) and electronic cigarette
(ePen 3). In addition, we compared the commonly used test matrices for tobacco and nicotine …
(ePen 3). In addition, we compared the commonly used test matrices for tobacco and nicotine …
[HTML][HTML] In vitro toxicological evaluation of aerosols generated by a 4th generation vaping device using nicotine salts in an air-liquid interface system
… Ten e-liquids were analysed sequentially to cover a wide range of e-liquid compositions
and to evaluate the specific toxicological impact of each ingredientinvolved in the formulation (…
and to evaluate the specific toxicological impact of each ingredientinvolved in the formulation (…
[HTML][HTML] An approach for the extract generation and toxicological assessment of tobacco-free 'modern'oral nicotine pouches
E Bishop, N East, S Bozhilova, S Santopietro… - … and chemical toxicology, 2020 - Elsevier
… 1R6F demonstrated toxicological responses in most assays; … of MOPs extracts and their
toxicological evaluation using in vitro … There are many formulations of AS depending on the …
toxicological evaluation using in vitro … There are many formulations of AS depending on the …
Evaluation of nicotine and the components of e-liquids generated from e-cigarette aerosols
MR Peace, HA Mulder, TR Baird… - … Analytical Toxicology, 2018 - academic.oup.com
… In order to control variability from purchased e-liquids and to develop a model for comparisons,
a formulation of 50:50 PG:VG with 12 mg/mL nicotine was used at all voltages in this …
a formulation of 50:50 PG:VG with 12 mg/mL nicotine was used at all voltages in this …
Bridging inhaled aerosol dosimetry to physiologically based pharmacokinetic modeling for toxicological assessment: nicotine delivery systems and beyond
… formulations, NRTs were unable to mimic the plasma concentrations of nicotine following
inhalation, as the absorption of nicotine … evaluated the relationship between plasma nicotine …
inhalation, as the absorption of nicotine … evaluated the relationship between plasma nicotine …
[HTML][HTML] Assessing modified risk tobacco and nicotine products: description of the scientific framework and assessment of a closed modular electronic cigarette
J Murphy, M Gaca, F Lowe, E Minet, D Breheny… - Regulatory Toxicology …, 2017 - Elsevier
… of the tobacco consumable may be required to evaluate … formulation used in these studies
was the commercially available Blended Tobacco formulation containing 1.86% v/v nicotine (…
was the commercially available Blended Tobacco formulation containing 1.86% v/v nicotine (…
[HTML][HTML] Comparative in vitro toxicity profile of electronic and tobacco cigarettes, smokeless tobacco and nicotine replacement therapy products: e-liquids, extracts and …
M Misra, RD Leverette, BT Cooper, MB Bennett… - International journal of …, 2014 - mdpi.com
… A great variety of e-cig sizes, configurations, liquid formulations … study evaluated the
toxicological impact of traditional tobacco … (tobacco cigarette, e-cig, SLT and NRT), the …
toxicological impact of traditional tobacco … (tobacco cigarette, e-cig, SLT and NRT), the …
[HTML][HTML] A Practical Framework for Novel Electronic Nicotine Delivery System Evaluation: Chemical and Toxicological Characterization of JUUL2 Aerosol and …
DK Cook, G Lalonde, MJ Oldham, J Wang, A Bates… - Toxics, 2024 - mdpi.com
… Utilizing the JUUL2 System, six pre-filled e-liquid formulations at an 18 mg/mL nicotine …
The in vitro toxicological evaluation was based upon the testing recommended for tobacco …
The in vitro toxicological evaluation was based upon the testing recommended for tobacco …
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