… smoke toxins. Our finding of impaired metabolism of nicotine while mentholated cigarette
smoking suggests that mentholated cigarette smoking enhances systemic nicotine exposure. …

… to metabolic effects of smoking as … cigarette smoking on metabolic rate to determine the
existence and magnitude of such an effect. Because nicotine is the component of tobacco smoke …

… This study confirms previous observations that cigarette smoking inhibits nicotine metabolism
… must be considered in understanding the effects of cigarette smoking on drug metabolism. …

… of nicotine was unaltered as a result of chronic smoking 1 … that cigarette smoking accelerated
nicotine metabolism [ 140, … whether nicotine metabolism was induced in cigarette smokers. …

… less 5 , 6 whereas those with increased metabolism smoke more. However, … nicotine
metabolism among smokers with functional wild-type alleles of CYP2A6. The metabolism of nicotine …

… The majority of nornicotine excreted by cigarette smokers is derived from NIC metabolism
even though up to 40% of nornicotine may come from tobacco per se [11]. Nornicotine has …

… concentrations and, as a consequence, reduced smoking behaviour. This review … drug
metabolism enzymes involved in nicotine metabolism and their potential influence on smoking …

… and resultant tobacco-related cancer risk. We compared the rate of nicotine metabolism and
the intake of nicotine per cigarette smoked among smokers of different ethnicities. Methods: …

… content per one cigarette, the depth of inhalation, and the force of drawing). We developed
… of nicotine metabolism to cotinine in non-smokers.If smokers could abstain from smoking for …

… nicotine is extensively metabolized in the liver to form a wide variety of metabolites including
nicotine N′-… of this study was to overview the biological effects and metabolism of nicotine. …