Molecular mechanisms and therapeutic strategies related to nitric oxide

S Moncada, EA Higgs - The FASEB journal, 1995 - Wiley Online Library
Nitric oxide plays a role in vivo as a regulator of smooth … Nitric oxide appears to inhibit the
NO synthase … Nitric oxide reacts with oxygen to form the toxic gas nitrogen dioxide. However, …

Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease.

JL Dinerman, CJ Lowenstein, SH Snyder - Circulation Research, 1993 - Am Heart Assoc
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing
factor… Molecular cloning and functional expression of an inducible nitric oxide synthase from a …

Molecular mechanisms for discrete nitric oxide levels in cancer

LA Ridnour, DD Thomas, C Switzer, W Flores-Santana… - Nitric oxide, 2008 - Elsevier
… wound responses by NO is an additional mechanism for the potentiation of chemo and
radiation therapies. Although molecular mechanisms regulating growth differ among cancer types…

Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

I Fleming, R Busse - American Journal of Physiology …, 2003 - journals.physiology.org
nitric oxide synthase (eNOS), the expression of which is regulated by a range of transcriptional
and posttranscriptional mechanisms, generates nitric oxide (… the endothelial nitric oxide

Molecular mechanisms of nitric oxide in cancer progression, signal transduction, and metabolism

V Somasundaram, D Basudhar… - Antioxidants & Redox …, 2019 - liebertpub.com
Nitric oxide (NO) plays specific roles within tumor cells and the microenvironment and …
evident that nitric oxide synthase 2 (NOS2)-mediated NO/reactive nitrogen oxide species (RNS) …

[HTML][HTML] Cytochrome c oxidase and nitric oxide in action: molecular mechanisms and pathophysiological implications

P Sarti, E Forte, D Mastronicola, A Giuffrè… - Biochimica et Biophysica …, 2012 - Elsevier
… IV (cytochrome c oxidase, CcOX) and nitric oxide (NO) were described in the early 60's. The
… The reactions of interest are reviewed, with special attention to the molecular mechanisms

Pharmacology of nitric oxide: molecular mechanisms and therapeutic strategies

R Domenico - Current pharmaceutical design, 2004 - ingentaconnect.com
Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J 1995; 9: …
Mechanism of suppression of nitric oxide expression by interleukin 4 in primary mouse …

Hemoglobin, nitric oxide and molecular mechanisms of hypoxic vasodilation

BW Allen, JS Stamler, CA Piantadosi - Trends in molecular medicine, 2009 - cell.com
… that nitric oxide (NO) is a biological signaling molecule, … ubiquitous molecule, has reawakened
the search for mechanisms … on the presence of endothelial nitric oxide synthase (eNOS). …

The basics about nitric oxide

R Bruckdorfer - Molecular aspects of medicine, 2005 - Elsevier
Nitric oxide is a gas and a free radical which is now … tissues using the three isoforms of nitric
oxide synthase, one of which is … in the primary defence mechanisms against attack by micro-…

Nitric oxide regulation of mitochondrial oxygen consumption II: molecular mechanism and tissue physiology

CE Cooper, C Giulivi - American Journal of Physiology-Cell …, 2007 - journals.physiology.org
Nitric oxide (NO) is an intercellular signaling molecule; … This review describes the molecular
mechanism of this interaction and … nitric oxide (NO) is known as an intercellular messenger, …