The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
… NLRP3 inflammasome in COVID-19, this review describes the possible pathways of NLRP3
inflammasome activation … the NLRP3 inflammasome in the pathogenesis of COVID-19 and …
inflammasome activation … the NLRP3 inflammasome in the pathogenesis of COVID-19 and …
[HTML][HTML] Severe COVID-19: NLRP3 inflammasome dysregulated
DF Van den Berg, AA Te Velde - Frontiers in immunology, 2020 - frontiersin.org
… role of NLRP3 inflammasome activation in the severe symptomatic phase of COVID-19 and
… In search for a pathway to relate sustained NLRP3 inflammasome activation in aging we …
… In search for a pathway to relate sustained NLRP3 inflammasome activation in aging we …
[HTML][HTML] Targeting the NLRP3 inflammasome in severe COVID-19
TL Freeman, TH Swartz - Frontiers in immunology, 2020 - frontiersin.org
… -containing 3 (NLRP3) inflammasome pathway and … COVID-19 and NLRP3 activation
and describe an important role in targeting this pathway for the treatment of severe COVID-19…
and describe an important role in targeting this pathway for the treatment of severe COVID-19…
[HTML][HTML] Novel coronavirus-induced NLRP3 inflammasome activation: a potential drug target in the treatment of COVID-19
A Shah - Frontiers in immunology, 2020 - frontiersin.org
… NLRP3 inflammasome appears to be a potential drug target in the treatment of coronavirus
disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3 inflammasome …
disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3 inflammasome …
[HTML][HTML] The inflammasome in times of COVID-19
… COVID-19 patients. Here we review the literature regarding the mechanism of inflammasome
activation … , it seems that ORF3a promotes NLRP3 inflammasome activation by modulating …
activation … , it seems that ORF3a promotes NLRP3 inflammasome activation by modulating …
Inflammasome activation in COVID-19 patients
… has been highly speculated, the inflammasome activation and participation in the … NLRP3
inflammasome is activated in response to SARS-CoV-2 infection and it is active in COVID-19, …
inflammasome is activated in response to SARS-CoV-2 infection and it is active in COVID-19, …
[HTML][HTML] NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity
… In this review, we focused on the occurrence of NLRP3 inflammasome activation in … interlink
between NLRP3 inflammasome activation and underlying conditions of COVID-19 severity, …
between NLRP3 inflammasome activation and underlying conditions of COVID-19 severity, …
[HTML][HTML] Inflammasome activation at the crux of severe COVID-19
… cytosolic Ca 2+ influx to activate NLRP3 in reconstituted Vero epithelial cells 113,114 .
Another mechanism of NLRP3 inflammasome activation involves direct interactions with viral …
Another mechanism of NLRP3 inflammasome activation involves direct interactions with viral …
[HTML][HTML] Nutraceutical strategies for suppressing NLRP3 inflammasome activation: pertinence to the management of COVID-19 and beyond
MF McCarty, SB Iloki Assanga, L Lewis Luján… - Nutrients, 2020 - mdpi.com
… to inhibit NLRP3 inflammasome activation via interaction … useful in the cytokine storm phase
of COVID-19 [266,267,268]. … activation of NLRP3-dependent inflammasome activation by …
of COVID-19 [266,267,268]. … activation of NLRP3-dependent inflammasome activation by …
[HTML][HTML] Common NLRP3 inflammasome inhibitors and Covid-19: divide and conquer
… 2 may be linked to NLRP3 inflammasome activation which has … In SARS-CoV-2 infection,
NLRP3 inflammasome activation … selective inhibitors of NLRP3 inflammasome. To achieve this, …
NLRP3 inflammasome activation … selective inhibitors of NLRP3 inflammasome. To achieve this, …
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