过去一年中添加的文章,按日期排序
Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy
T Liu, Y Hao, Q Mao, N Zhou, M Liu, J Wu… - Chinese Journal of …, 2024 - Springer
17 天前 - … TRQ could reduce the level of mtROS by promoting mitophagy in macrophages
infected with influenza A virus, thus inhibiting the activation of NLRP3 inflammasome and the …
infected with influenza A virus, thus inhibiting the activation of NLRP3 inflammasome and the …
[HTML][HTML] DUSP1 Mitigates MSU-Induced Immune Response in Gouty Arthritis Reinforcing Autophagy
J Nie, H Qiu - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
20 天前 - … This study identified a novel role for DUSP1 as a suppressor of NLRP3 inflammasome
activation via the enhancement of autophagy in MSU-induced GA. DUSP1 expression …
activation via the enhancement of autophagy in MSU-induced GA. DUSP1 expression …
Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis
B Li, P Li, L Wei, J Zou, Y Wang, Q You… - Journal of Medicinal …, 2024 - ACS Publications
22 天前 - … To find new therapeutic targets, … activation of the NLRP3 inflammasome can lead
to various inflammatory and autoimmune diseases, making it an ideal target for RA treatment. …
to various inflammatory and autoimmune diseases, making it an ideal target for RA treatment. …
Pyroptosis: palmitoylation regulates GSDMD activation and pore formation
E Hartenian, P Broz - Cell Research, 2024 - nature.com
22 天前 - … upon nigericin-induced activation of the NLRP3 inflammasome in human THP-1 …
Intriguingly, GSDMD deficiency reduced ROS production upon inflammasome activation…
Intriguingly, GSDMD deficiency reduced ROS production upon inflammasome activation…
PDIA4 Suppresses the NLRP3 Inflammasome and Pyroptosis in Renal Tubules by Modulating the IRE1α/sXBP1 Pathway in Diabetic Kidney Disease
X Liu, D Zhou, Y Su, H Liu, Q Su, T Shen… - Available at SSRN … - papers.ssrn.com
22 天前 - … induced IRE1α signaling, thereby reducing the activation of the NLRP3 inflammasome
and 326 pyroptosis, highlighting its potential as a therapeutic target in diabetic kidney …
and 326 pyroptosis, highlighting its potential as a therapeutic target in diabetic kidney …
Platelets in Kawasaki disease: mediators of vascular inflammation
M Noval Rivas, B Kocatürk, BS Franklin… - Nature Reviews …, 2024 - nature.com
23 天前 - … NLRP3 inflammasome activation and IL-1β production by human immune cells by
releasing soluble mediators. Activated … therapeutic targets for Kawasaki disease vasculitis. …
releasing soluble mediators. Activated … therapeutic targets for Kawasaki disease vasculitis. …
[HTML][HTML] Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury
S Gastaldi, M Giordano, F Blua, C Rubeo… - Vascular …, 2024 - Elsevier
23 天前 - … Several factors contribute to ischemia/reperfusion injury (IRI), including activation
of the NLRP3 inflammasome and its byproducts, such as interleukin-1β (IL-1β) and caspase-1…
of the NLRP3 inflammasome and its byproducts, such as interleukin-1β (IL-1β) and caspase-1…
Platelets in Kawasaki disease: mediators of vascular inflammation.
B Kocatürk, BS Franklin, M Arditi - Nature reviews. Rheumatology, 2024 - europepmc.org
23 天前 - … NLRP3 inflammasome activation and IL-1β production by human immune cells by
releasing soluble mediators. Activated … vasculitis and therapeutic strategies targeting platelets …
releasing soluble mediators. Activated … vasculitis and therapeutic strategies targeting platelets …
The NLRP3 inflammasome mediates neurodegeneration in an ischemia-reperfusion injury model of acute angle-closure glaucoma
AR Griswold, SB Dickman, V McGilligan… - … & Visual Science, 2024 - iovs.arvojournals.org
23 天前 - … of the NLRP3 inflammasome is neuroprotective in a model of IOP-induced I/R
injury, identifying the NLRP3 inflammasome as a therapeutic target for the treatment of acute …
injury, identifying the NLRP3 inflammasome as a therapeutic target for the treatment of acute …
The inflammasome pathway is activated in experimental autoimmune uveitis
A Shome, ID Rupenthal, RL Niederer… - … & Visual Science, 2024 - iovs.arvojournals.org
23 天前 - … inflammasomes. However, the nucleotide-binding oligomerisation domain and
leucine-rich repeat receptor-3 (NLRP3) inflammasome … the NLRP3 inflammasome pathway also …
leucine-rich repeat receptor-3 (NLRP3) inflammasome … the NLRP3 inflammasome pathway also …