过去一年中添加的文章,按日期排序

Tanreqing Injection Inhibits Activation of NLRP3 Inflammasome in Macrophages Infected with Influenza A Virus by Promoting Mitophagy

T Liu, Y Hao, Q Mao, N Zhou, M Liu, J Wu… - Chinese Journal of …, 2024 - Springer
17 天前 - … TRQ could reduce the level of mtROS by promoting mitophagy in macrophages
infected with influenza A virus, thus inhibiting the activation of NLRP3 inflammasome and the …

[HTML][HTML] DUSP1 Mitigates MSU-Induced Immune Response in Gouty Arthritis Reinforcing Autophagy

J Nie, H Qiu - Frontiers in Bioscience-Landmark, 2024 - imrpress.com
20 天前 - … This study identified a novel role for DUSP1 as a suppressor of NLRP3 inflammasome
activation via the enhancement of autophagy in MSU-induced GA. DUSP1 expression …

Discovery and Development of NLRP3 Inhibitors Targeting the LRR Domain to Disrupt NLRP3-NEK7 Interaction for the Treatment of Rheumatoid Arthritis

B Li, P Li, L Wei, J Zou, Y Wang, Q You… - Journal of Medicinal …, 2024 - ACS Publications
22 天前 - … To find new therapeutic targets, … activation of the NLRP3 inflammasome can lead
to various inflammatory and autoimmune diseases, making it an ideal target for RA treatment. …

Pyroptosis: palmitoylation regulates GSDMD activation and pore formation

E Hartenian, P Broz - Cell Research, 2024 - nature.com
22 天前 - … upon nigericin-induced activation of the NLRP3 inflammasome in human THP-1 …
Intriguingly, GSDMD deficiency reduced ROS production upon inflammasome activation

PDIA4 Suppresses the NLRP3 Inflammasome and Pyroptosis in Renal Tubules by Modulating the IRE1α/sXBP1 Pathway in Diabetic Kidney Disease

X Liu, D Zhou, Y Su, H Liu, Q Su, T Shen… - Available at SSRN … - papers.ssrn.com
22 天前 - … induced IRE1α signaling, thereby reducing the activation of the NLRP3 inflammasome
and 326 pyroptosis, highlighting its potential as a therapeutic target in diabetic kidney …

Platelets in Kawasaki disease: mediators of vascular inflammation

M Noval Rivas, B Kocatürk, BS Franklin… - Nature Reviews …, 2024 - nature.com
23 天前 - NLRP3 inflammasome activation and IL-1β production by human immune cells by
releasing soluble mediators. Activatedtherapeutic targets for Kawasaki disease vasculitis. …

[HTML][HTML] Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury

S Gastaldi, M Giordano, F Blua, C Rubeo… - Vascular …, 2024 - Elsevier
23 天前 - … Several factors contribute to ischemia/reperfusion injury (IRI), including activation
of the NLRP3 inflammasome and its byproducts, such as interleukin-1β (IL-1β) and caspase-1…

Platelets in Kawasaki disease: mediators of vascular inflammation.

B Kocatürk, BS Franklin, M Arditi - Nature reviews. Rheumatology, 2024 - europepmc.org
23 天前 - NLRP3 inflammasome activation and IL-1β production by human immune cells by
releasing soluble mediators. Activated … vasculitis and therapeutic strategies targeting platelets …

The NLRP3 inflammasome mediates neurodegeneration in an ischemia-reperfusion injury model of acute angle-closure glaucoma

AR Griswold, SB Dickman, V McGilligan… - … & Visual Science, 2024 - iovs.arvojournals.org
23 天前 - … of the NLRP3 inflammasome is neuroprotective in a model of IOP-induced I/R
injury, identifying the NLRP3 inflammasome as a therapeutic target for the treatment of acute …

The inflammasome pathway is activated in experimental autoimmune uveitis

A Shome, ID Rupenthal, RL Niederer… - … & Visual Science, 2024 - iovs.arvojournals.org
23 天前 - inflammasomes. However, the nucleotide-binding oligomerisation domain and
leucine-rich repeat receptor-3 (NLRP3) inflammasome … the NLRP3 inflammasome pathway also …