过去一年中添加的文章，按日期排序
[HTML][HTML] The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation
D Ehirchiou, I Bernabei… - … & Therapy, 2024 - arthritis-research.biomedcentral.com
29 天前 - … receptor that modulates NLRP3 inflammasome activation by MSU crystal in
macrophages, which could be a potential therapeutic target to treat gouty arthritis in human patients. …
macrophages, which could be a potential therapeutic target to treat gouty arthritis in human patients. …
The role and mechanism of pyroptosis and potential therapeutic targets in non-alcoholic fatty liver disease (NAFLD)
SJ Li, AB Liu, YY Yu, JH Ma - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
30 天前 - … NLRP3 inflammasome activation can boost the activation of pro-caspase-1 and
the release of key inflammatory factors, which is vital for the initiation and development of …
the release of key inflammatory factors, which is vital for the initiation and development of …
[HTML][HTML] FAM3A plays a key role in protecting against tubular cell pyroptosis and acute kidney injury
X Li, F Yuan, Y Xiong, Y Tang, Z Li, J Ai, J Miao, W Ye… - Redox Biology, 2024 - Elsevier
32 天前 - … sensed the overload of mt-ROS and then activated Caspase-1, … FAM3A is a potential
therapeutic target for treating AKI. … Of note, NLRP3 inflammasome activation, inflammation, …
therapeutic target for treating AKI. … Of note, NLRP3 inflammasome activation, inflammation, …
Inhibition of NLRP3 inflammasome alleviates cognitive deficits in a mouse model of anti-NMDAR encephalitis induced by active immunization
X Yang, A Sun, L Kong, X Yang, X Zhao… - International …, 2024 - Elsevier
33 天前 - … Schematic illustration of the activated NLRP3 inflammasome and the therapeutic
effects of … Thus, NLRP3 inflammasome may appear to be a potential therapeutic target for anti-…
effects of … Thus, NLRP3 inflammasome may appear to be a potential therapeutic target for anti-…
[HTML][HTML] Role of NLRP3 inflammasome in central nervous system diseases
L Zhang, Y Tang, P Huang, S Luo, Z She… - Cell & …, 2024 - ncbi.nlm.nih.gov
33 天前 - … of NLRP3 inflammasome, summarize the recent advances and clinical impact of the
NLRP3 inflammasome … and challenges of NLRP3 as a therapeutic target for CNS diseases. …
NLRP3 inflammasome … and challenges of NLRP3 as a therapeutic target for CNS diseases. …
[HTML][HTML] A Dynamic Protocol to Explore NLRP3 Inflammasome Activation in Cerebral Organoids
D El Soufi El Sabbagh, L Attisano… - International Journal of …, 2024 - mdpi.com
33 天前 - … Inducing NLRP3 inflammasome activation in cell culture is a two-step process which
… a priming and activation step [25]. Specifically, the first step involves treatment with LPS …
… a priming and activation step [25]. Specifically, the first step involves treatment with LPS …
[HTML][HTML] Molecular Aspects of Inflammation and Lipid Metabolism in Health and Disease: The Role of the Mitochondria
VN Sukhorukov, AN Orekhov - International Journal of Molecular …, 2024 - mdpi.com
33 天前 - … the identification of new therapeutic targets for patients with … a role in inflammasome
activation by releasing DAMPs … such as the activation of the NLRP3 inflammasome and the …
activation by releasing DAMPs … such as the activation of the NLRP3 inflammasome and the …
Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss
J Fang, Z Li, P Wang, X Zhang, S Mao, Y Li… - Neural Regeneration … - journals.lww.com
33 天前 - … To our knowledge, this is the first study to verify the roles of pyroptosis and
inflammasome activation in SGN degeneration. Our results showed NLRP3 inflammasome activation …
inflammasome activation in SGN degeneration. Our results showed NLRP3 inflammasome activation …
[HTML][HTML] Activation of the Macrophage-Associated Inflammasome Exacerbates Myocardial Fibrosis Through the 15-HETE-Mediated Pathway in Acute Myocardial …
X Chen, Z Du, D Guo, J Guo, Q Sun, T Liu, K Hua, C Li… - Engineering, 2024 - Elsevier
34 天前 - … -associated NLRP3 inflammasome activation and myocardial fibrosis, we employed
targeted … These findings revealed that macrophage-associated inflammasome activation …
targeted … These findings revealed that macrophage-associated inflammasome activation …
[PDF][PDF] Multiple sclerosis: the NLRP3 inflammasome, gasdermin D, and
A Brint, S Greene, AR Fennig-Victor, S Wang - 2024 - cdn.amegroups.cn
34 天前 - … inflammation in MS, therapeutics targeting these inflammatory processes … the
NLRP3 inflammasome induces such pathways and the potential intervention points for therapeutic …
NLRP3 inflammasome induces such pathways and the potential intervention points for therapeutic …