58 天前 - … Importantly, we sought to achieve a deeper understanding of the NLRP3
inflammasome with the ultimate goal of identifying potential therapeutic targets for SAE. …

58 天前 - … However, whether NLRP3 inflammasome activation … PLUNC and NLRP3
inflammasome activation during NPC … by inhibiting the activation of the NLRP3 inflammasome, …

61 天前 - … Macrophage α7nAChR activation mitigates NLRP3 inflammasome activation by
modulating mTOR phosphorylation, and subsequently alleviates intestinal inflammation and …

61 天前 - … Recent work has also shown that NLRP3 inflammasome activation occurs as a result
of … as potential therapeutic targets in ACVD and offers support for the idea that genetically …

61 天前 - … and cell pyroptosis linked to NLRP3 inflammasome in HK-2 … leading to the activation
of the NLRP3 inflammasome and … results may provide new perspectives on DKD treatment. …

62 天前 - … , aiming to identify effective therapeutic targets. Here, we … Rab11b specifically
activated the NLRP3 inflammasome in … specifically inhibit NLRP3 inflammasome activation, and …

62 天前 - … SMS also abolished NLRP3 inflammasome activation and inhibited subsequent
caspase-1 activation and IL-1β secretion, suggesting a new therapeutic target for the treatment …

62 天前 - … Moreover, prodrugs, which selectively release the drug in the target tissue, have
been … NLRP3 inflammasome activation and their potential use against NLRP3 inflammasome …

62 天前 - … their inhibition on NLRP3 activation and NLRP3 inflammasome formation. Of
these three, … NLRP3 is emerging as an attractive therapeutic target to modulate the IL-1-mediated …

63 天前 - … activated NLRP3 inflammasome in BMDMs under ATP and nigericin stimulation
conditions after treatment … inhibited the activation of NLRP3 inflammasome induced by ATP and …