… In this article, we review the recent findings of NLRP3 inflammasome, speculate its possible
… challenges in targeting NLRP3 inflammasome for AD therapy. Inflammasomes: Platforms for …

… regulatory mechanisms of the NLRP3 inflammasome in the pathogenic … NLRP3 inflammasome
for AD. Further clarification of the regulatory mechanisms of the NLRP3 inflammasome in …

… In this review, we will primarily discuss the role of inflammasome activation by microglia
in Alzheimer's disease with a special focus on Nlrp3 inflammasome activation. …

… of NLRP3 inflammasome activity … NLRP3 activation, but tau fibrils did not. In addition, fibrillar
Aβ facilitated tau pathology by activating NLRP3, indicating that the NLRP3 inflammasome …

… Monocytes co-expressing NLRP3 with caspase 1 or caspase … NLRP3 with PYCARD were
augmented in both severe and MILD AD. Activation of the NLRP1 and NLRP3 inflammasomes …

… by which the activation of NLRP3 inflammasomes affects the pathogenesis of AD, and the …
NLRP3 inflammasomes. By researching the activation or inactivation of NLRP3 inflammasome…

… disease. In the current review, we summarize the generally accepted mechanisms of NLRP3
inflammasome … possible roles of microglia-specific NLRP3 activation in AD pathogenesis, …

… druggable potential of the NLRP3 inflammasome. Herein we review the NLRP3 inflammasome
and its role in AD, from the mechanisms of NLRP3 activation to downstream inflammatory …

… In this study, we found that gut microbiota in AD patients could induce the activation of
NLRP3 inflammasome in the intestinal tract of mice, subsequently causing the release of …

… Given that we demonstrated the activation of NLRP3 inflammasome in the TgCRND8 mice,
we next determined whether JC-124 could inhibit NLRP3 inflammasome signaling and exert …