Oxytocin inhibits the membrane depolarization-induced increase in intracellular calcium in capsaicin sensitive sensory neurons: a peripheral mechanism of analgesic …

S Hobo, K Hayashida, JC Eisenach - Anesthesia & Analgesia, 2012 - journals.lww.com
… A majority of small diameter neurons in this preparation respond to the TRPV1 receptor
agonist, capsaicin, 25 and are presumed nociceptors, so we tested the effect of oxytocin on 21 …

Contribution of TRPV1 to the bradykinin-evoked nociceptive behavior and excitation of cutaneous sensory neurons

K Katanosaka, RK Banik, R Giron, T Higashi… - Neuroscience …, 2008 - Elsevier
… BK clearly increased intracellular calcium in cultured dorsal root ganglion (DRG) neurons of
… of the sensory neurons in a much larger population, we observed calcium responses in the …

Mode of action of cytokines on nociceptive neurons

N Üçeyler, M Schäfers, C Sommer - Experimental brain research, 2009 - Springer
… lower temperatures without altering intracellular calcium levels. This IL-1β-induced heat
sensitization is mediated by activation of protein kinases. IL-1 receptor is expressed on DRG …

[HTML][HTML] The calcium channel α2δ1 subunit: Interactional targets in primary sensory neurons and role in neuropathic pain

W Cui, H Wu, X Yu, T Song, X Xu, F Xu - Frontiers in Cellular …, 2021 - frontiersin.org
… of the nociceptive pathway in primary sensory neurons. Currently, … intracellular Ca 2+
homeostasis in primary sensory neurons of … Ca 2+ influx and buffering. This process involves the …

Complex regulation of capsaicin on intracellular second messengers by calcium dependent and independent mechanisms in primary sensory neurons

Y Xu, J Zhang, L Li, Z Ye, Y Zhang, X Gao, F Li… - Neuroscience …, 2012 - Elsevier
… the different Ca 2+ -dependency underlying capsaicin's effects on the intracellular second
… for the sensitizing or desensitizing of nociceptors in rat trigeminal ganglion (TG) neurons. …

Mutual influence of plasma membrane structures and intracellular calcium stores on the formation of calcium signals in primary nociceptive neurons

IV Stepanova, EP Kostyuk, PG Kostyuk - … (Moscow) Supplement Series A …, 2007 - Springer
calcium-regulating mechanisms in the formation of intracellular calcium signals in rat primary
sensory neurons … Mitochondria were shown to be the most powerful intracellular calcium-…

Pre‐ and postsynaptic contributions of voltage‐dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neurons

B Heinke, E Balzer, J Sandkühler - European journal of …, 2004 - Wiley Online Library
Ca 2+ increase in lamina I neurons and to the synaptic transmission between nociceptive
afferents and second order neurons in … gives rapid rise in intracellular Ca 2+ concentration. …

Inhibition of N-type voltage-activated calcium channels in rat dorsal root ganglion neurons by P2Y receptors is a possible mechanism of ADP-induced analgesia

Z Gerevich, SJ Borvendeg, W Schröder… - Journal of …, 2004 - Soc Neuroscience
… The main finding here is that P2Y 1 receptor activation inhibits VACCs and the subsequent
increase of the intracellular Ca 2+ concentration in small nociceptive DRG neurons of rats. It …

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons

H Cho, YD Yang, J Lee, B Lee, T Kim, Y Jang… - Nature …, 2012 - nature.com
Nociceptors are a subset of small primary afferent neurons that respond to noxious chemical,
thermal and mechanical stimuli. Ion channels in nociceptors respond differently to noxious …

Mechanical stimuli induce intracellular calcium response in a subpopulation of cultured rat sensory neurons

H Gotoh, A Takahashi - Neuroscience, 1999 - Elsevier
… which corresponds to the tactile neuron, and the other is a broad spike with a high threshold
which corresponds to the nociceptive neuron. Polymodal nociceptors respond to both high-…