The effect of polyamines on endomycorrhizal infection of wild-type Pisum sativum, cv. Frisson (nod+myc+) and two mutants (nod myc+ and nodmyc)

NE Ghachtouli, M Paynot, D Morandi, J Martin-Tanguy… - Mycorrhiza, 1995 - Springer
… In the present study, we report the presence of the free polyamines Put, Cad, Spd, and
Spin in … (nod +myc +) and two isogenic mutants of this cultivar, P56 (nod-myc § and P2 (nod-myc-). …

Myc, oncogenic protein translation, and the role of polyamines

AT Flynn, MD Hogarty - Medical Sciences, 2018 - mdpi.com
… to increase polyamines in proliferative tissues, and this is further augmented in the many …
hyperactivated MYC. In this review, we discuss MYC-driven regulation of polyamines and …

Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells

P Celano, SB Baylin, RAJ Casero - Journal of Biological Chemistry, 1989 - ASBMB
… of c-myc mRNA suggested that the effect of polyamine depletion on cmyc mRNA levels …
suggest that variations in polyamine concentration could play a critical role in modulating gene …

PGC1α inhibits polyamine synthesis to suppress prostate cancer aggressiveness

L Kaminski, S Torrino, M Dufies, Z Djabari, R Haider… - Cancer research, 2019 - AACR
… In this study, we demonstrate that PGC1α is the regulator of a c-MYC–driven onco-metabolic
pathway that promotes prostate cancer aggressiveness through the polyamine pathway. …

MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion

MD Chalishazar, SJ Wait, F Huang, AS Ireland… - Clinical Cancer …, 2019 - AACR
… target, and we found Odc1 is a consistently upregulated polyamine pathway enzyme in
MYC-driven SCLC, so further studies warrant determining whether ODC1 is the critical target …

Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma

BS Park, H Jeon, Y Kim, H Kwon, GE Choi, SG Chi… - Molecular Cancer, 2024 - Springer
… of c-Myc is responsible for the activation of polyamine synthesis in vemurafenib-resistant
cancer. Inhibition of polyamine biosynthesis, EIF5A hypusination, or c-Myc suppressed …

Role of polyamines and hypusine in β cells and diabetes pathogenesis

A Kulkarni, CM Anderson, RG Mirmira, SA Tersey - Metabolites, 2022 - mdpi.com
polyamines control β-cell replication via regulating c-Myc activity [14]. Specific roles of individual
… In the non-obese diabetic (NOD) mouse model of spontaneous T1D, it was shown that …

Polyamines and flavonoids: key compounds in mycorrhizal colonization of improved and unimproved soybean genotypes

MS Salloum, MF Menduni, MP Benavides, M Larrauri… - Symbiosis, 2018 - Springer
… Flavonoids and polyamines (PAs) are hypothesized to play a role in this symbiosis. We
tested the effects of them in AMF roots of improved (I-1) and unimproved (UI-4) soybean …

Polyamine-dependent early cellular signals and cell proliferation

SM Oredsson - Polyamine Cell Signaling: Physiology, Pharmacology …, 2006 - Springer
… to a specific role for polyamines regarding c-myc and c-jun … -fos and c-myc were decreased
in polyamine-depleted nuclei … the mechanisms by which polyamines modulate cell growth. …

Polyamine-dependent gene expression

AC Childs, DJ Mehta, EW Gerner - Cellular and Molecular Life Sciences …, 2003 - Springer
… on proteolytic enzymes and pathways or modulate their function indirectly still remains …
polyamines, polyamine synthesis inhibitors and polyamine analogs on casein kinase II using Myc