Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the next pertussis vaccine
JB ROBBINS, M PITTMAN, B TROLLFORS… - The Pediatric …, 1993 - journals.lww.com
… reduces but does not eliminate the activity of pertussis toxin. Complete … of pertussis toxin
and is not a suitable vaccine (RSekura, personal communication). Why was pertussis toxin not …
and is not a suitable vaccine (RSekura, personal communication). Why was pertussis toxin not …
A placebo-controlled trial of a pertussis-toxoid vaccine
B Trollfors, J Taranger, T Lagergård… - … England Journal of …, 1995 - Mass Medical Soc
… Since only two doses were given and the children were 6 to 11 months of age when admitted
to the trial, valid comparisons with the pertussis toxoid used in our study are not possible. …
to the trial, valid comparisons with the pertussis toxoid used in our study are not possible. …
A toxoid vaccine for pertussis as well as diphtheria? Lessons to be relearned
R Schneerson, JB Robbins, J Taranger, T Lagergard… - The Lancet, 1996 - thelancet.com
… of pertussis toxoid is generally agreed. The use of a monocomponent pertussis vaccine has
… Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the next …
… Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the next …
Pertussis vaccine: a critique
JB Robbins, R Schneerson, JM Keith… - The Pediatric …, 2009 - journals.lww.com
… no statistically significant difference between the efficacy of multicomponent vaccines compared
with that of pertussis toxoid … s) does not add to the immunity conferred by pertussis toxoid …
with that of pertussis toxoid … s) does not add to the immunity conferred by pertussis toxoid …
Immunologic and epidemiologic experience of vaccination with a monocomponent pertussis toxoid vaccine
J Taranger, B Trollfors, E Bergfors, N Knutsson… - …, 2001 - publications.aap.org
… -pertussis toxin does not kill or inactivate B pertussis. Our best explanation is that anti-pertussis
toxin … Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the …
toxin … Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the …
… Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussisin Mice
IP Nascimento, WO Dias, RP Mazzantini… - Infection and …, 2000 - Am Soc Microbiol
… , a recombinant BCG-pertussis vaccine could be a more … genetically detoxified S1 subunit
of pertussis toxin 9K/129G (… as increased proliferation, upon pertussis toxin (PT) stimulation, …
of pertussis toxin 9K/129G (… as increased proliferation, upon pertussis toxin (PT) stimulation, …
The diphtheria and pertussis components of diphtheria-tetanus toxoids-pertussis vaccine should be genetically inactivated mutant toxins
JB Robbins, R Schneerson, B Trollfors… - The Journal of …, 2005 - academic.oup.com
… that pertussis toxoid is essential, but protective antibody levels for the non-pertussis toxin
(PT) components (filamentous hemagglutinin [FHA], pertactin, and fimbriae) have not been …
(PT) components (filamentous hemagglutinin [FHA], pertactin, and fimbriae) have not been …
From whole cell to acellular pertussis vaccines
RJL Willems, FR Mooi - Reviews and Research in Medical …, 1996 - journals.lww.com
… a pertussis vaccine composed solely of pertussis toxin will result in the emergence of B.
pertussis strains with silent pertussis toxin … non nocere: a pharmacologically inert pertussis toxoid …
pertussis strains with silent pertussis toxin … non nocere: a pharmacologically inert pertussis toxoid …
Pertussis: current concepts of pathogenesis and prevention
EL Hewlett - The Pediatric infectious disease journal, 1997 - journals.lww.com
… pertussis, which include the putative adhesins filamentous hemagglutinin, pertactin and
fimbriae, and pertussis toxin could … pertussis than vaccines containing only inactivated pertussis …
fimbriae, and pertussis toxin could … pertussis than vaccines containing only inactivated pertussis …
Cell-mediated and antibody responses to Bordetella pertussis antigens in children vaccinated with acellular or whole-cell pertussis vaccines
A Cassone, CM Ausiello, F Urbani… - … of pediatrics & …, 1997 - jamanetwork.com
… pertussis antigens (pertussis toxin, filamentous hemagglutinin, and pertactin). Antibody titers
against pertussis toxin… Results: A CMI-positive response to at least 1 B pertussis antigen at 1 …
against pertussis toxin… Results: A CMI-positive response to at least 1 B pertussis antigen at 1 …
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