… reduces but does not eliminate the activity of pertussis toxin. Complete … of pertussis toxin
and is not a suitable vaccine (RSekura, personal communication). Why was pertussis toxin not …

… Since only two doses were given and the children were 6 to 11 months of age when admitted
to the trial, valid comparisons with the pertussis toxoid used in our study are not possible. …

… of pertussis toxoid is generally agreed. The use of a monocomponent pertussis vaccine has
… Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the next …

… no statistically significant difference between the efficacy of multicomponent vaccines compared
with that of pertussis toxoid … s) does not add to the immunity conferred by pertussis toxoid …

… -pertussis toxin does not kill or inactivate B pertussis. Our best explanation is that anti-pertussis
toxin … Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the …

… , a recombinant BCG-pertussis vaccine could be a more … genetically detoxified S1 subunit
of pertussis toxin 9K/129G (… as increased proliferation, upon pertussis toxin (PT) stimulation, …

… that pertussis toxoid is essential, but protective antibody levels for the non-pertussis toxin
(PT) components (filamentous hemagglutinin [FHA], pertactin, and fimbriae) have not been …

… a pertussis vaccine composed solely of pertussis toxin will result in the emergence of B.
pertussis strains with silent pertussis toxin … non nocere: a pharmacologically inert pertussis toxoid …

… pertussis, which include the putative adhesins filamentous hemagglutinin, pertactin and
fimbriae, and pertussis toxin could … pertussis than vaccines containing only inactivated pertussis …

… pertussis antigens (pertussis toxin, filamentous hemagglutinin, and pertactin). Antibody titers
against pertussis toxin… Results: A CMI-positive response to at least 1 B pertussis antigen at 1 …