Primum non nocere: a pharmacologically inert pertussis toxoid alone should be the next pertussis vaccine

JB ROBBINS, M PITTMAN, B TROLLFORS… - The Pediatric …, 1993 - journals.lww.com
… a view of acellular pertussis vaccine development," which we believe is notvaccine-induced
protective immunity which are essential for the development of a safe and effective vaccine

The acellular pertussis vaccine trials: an interpretation

SA Plotkin, M Cadoz - The Pediatric infectious disease journal, 1997 - journals.lww.com
… for pertussis control as long ago as 1981, 6, 7 whereas in Sweden, Italy 8 and Germany (countries
that had largely abandoned pertussis vaccination … coping with endemic pertussis. …

Pertussis vaccine: a critique

JB Robbins, R Schneerson, JM Keith… - The Pediatric …, 2009 - journals.lww.com
… FHA does not confer additional protection to acellular pertussis … is no scientific basis for
including FHA in a pertussis vaccine. … best pertussis vaccine to our children as soon as possible. …

What Happened to Primum Non Nocere?

JB Seal, RS Daum - Pediatrics, 2001 - publications.aap.org
… , the importance of the birth dose was demonstrated in that children who received a first HBV
dose at birth were more likely to receive their first diphtheria, tetanus, and pertussis vaccine

Cell-mediated and antibody responses to Bordetella pertussis antigens in children vaccinated with acellular or whole-cell pertussis vaccines

A Cassone, CM Ausiello, F Urbani… - … of pediatrics & …, 1997 - jamanetwork.com
… response than the whole-cell vaccine, particularly against pertussis toxin. Once acquired, …
pertussis vaccine immunogenicity and a better correlate of long-term immunity to B pertussis

Reactions after pertussis vaccine.

LH Collier - British Medical Journal, 1978 - ncbi.nlm.nih.gov
… How often must we be reminded of the ancient precept "primum non nocere" ? … adverse
reactions associated with the use of Wellcome pertussis vaccine. He rightly draws attention to the …

The science and fiction of pertussis vaccines

JD Cherry, P Olin - Pediatrics, 1999 - publications.aap.org
… More importantly, the most efficacious DTaP vaccine is not … the immunization effort in this
and other countries. Our goal should be the eventual control of B pertussis infection and not just …

From whole cell to acellular pertussis vaccines

RJL Willems, FR Mooi - Reviews and Research in Medical …, 1996 - journals.lww.com
… ongoing pertussis vaccine efficacy trials will result in the introduction of an acellular … non
nocere: a pharmacologically inert pertussis toxoid alone should be the next pertussis vaccine

A placebo-controlled trial of a pertussis-toxoid vaccine

B Trollfors, J Taranger, T Lagergård… - … England Journal of …, 1995 - Mass Medical Soc
… There were no serious reactions. With the pertussis vaccine there were slightly more local
reactions than with the DT toxoids alone, but the rates of postvaccination fever were the same. …

A toxoid vaccine for pertussis as well as diphtheria? Lessons to be relearned

R Schneerson, JB Robbins, J Taranger, T Lagergard… - The Lancet, 1996 - thelancet.com
… The use of a monocomponent pertussis vaccine has been challenged because, as … non
nocere: a pharmacologically inert pertussis toxoid alone should be the next pertussis vaccine