Involvement of the Warburg effect in nontumor diseases processes

Z Chen, M Liu, L Li, L Chen - Journal of cellular physiology, 2018 - Wiley Online Library
… This review focuses on the newest researches about the role of Warburg effect in non-tumor
diseases… Obviously, Warburg effect may be a potential therapeutic target for those non-tumor

Metabolic implications of non-electrogenic ATP/ADP exchange in cancer cells: A mechanistic basis for the Warburg effect

JJ Lemasters - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2021 - Elsevier
… Overall, non-electrogenic ATP/ADP exchange promotes aerobic glycolysis (Warburg effect)
… do not, a phenomenon named the ‘Warburg effect’ by Efraim Racker in 1972, two years after …

Warburg effect and its role in tumourigenesis

MT Lebelo, AM Joubert, MH Visagie - Archives of pharmacal research, 2019 - Springer
… glucose when compared to non-tumourigenic cells (… non-tumourigenic liver tissue where
significantly less oxygen was used by the tumourigenic liver tissue when compared to the non-…

Regulation of glycolysis by non-coding RNAs in cancer: switching on the Warburg effect

H Mirzaei, MR Hamblin - Molecular Therapy-Oncolytics, 2020 - cell.com
The "Warburg effect" describes the reprogramming of glucose … of non-coding RNAs (ncRNAs)
are highlighted in several types of human cancer. ncRNAs, including microRNAs, long non-…

Warburg effect or reverse Warburg effect? A review of cancer metabolism

XD Xu, SX Shao, HP Jiang, YW Cao… - Oncology research and …, 2015 - karger.com
… the Warburg effect', has influenced and guided the study of the mechanism and treatment of
tumors … evidence and a new hypothesis, the reverse Warburg effect, has been put forward, in …

The emerging facets of non-cancerous Warburg effect

AM Abdel-Haleem, NE Lewis, N Jamshidi… - Frontiers in …, 2017 - frontiersin.org
… the cell’s unique feature of using the Warburg effect (WE), it is still unclear whether aerobic …
(8), relatively fewer studies have investigated the WE in non-cancerous cells (Figure 1). Here, …

The Warburg effect and the hallmarks of cancer

L Schwartz, CT Supuran… - Anti-Cancer Agents in …, 2017 - ingentaconnect.com
It is a longstanding debate whether cancer is one disease or a set of very diverse diseases.
The goal of this paper is to suggest strongly that most of (if not all) the hallmarks of cancer …

PDK1 promotes tumor cell proliferation and migration by enhancing the Warburg effect in non-small cell lung cancer

T Liu, H Yin - Oncology reports, 2017 - spandidos-publications.com
tumor cell glycolysis, we explored the function of PDK1 in regulating the Warburg effect. …
was performed to measure the PDK1 overexpression or knockdown effects (Fig. 4A and B). …

A critical review of the role of M2PYK in the Warburg effect

RA Harris, AW Fenton - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
… As a further contrast, a comparison of tumor tissue with non-tumor esophageal tissue
failed to identify the increase in glycolytic intermediates [156] that would be anticipated by the …

Mathematical modeling of the function of Warburg effect in tumor microenvironment

M Shamsi, M Saghafian, M Dejam, A Sanati-Nezhad - Scientific reports, 2018 - nature.com
… is known about how the Warburg effect affects tumor growth and progression. We … Warburg
effect on tumor morphology at day 30. In contrast to the non-glycolytic tumor, glycolytic tumors