… , and treatment targeting the NLRP3 inflammasome in the context of NAFLD progression. …
the NLRP3 inflammasome and summarize their pharmacological effectiveness for NAFLD …

… NLRP3 inflammasome … NLRP3 inflammasome activation by an orally available small
molecule inhibitor leads to the alleviation of the hepatic steatosis symptoms associated with NAFLD …

… been reported to decrease fatty degeneration of the liver. The … -fat diet-induced non-alcoholic
fatty liver disease (NAFLD) in mice through inhibiting the NLRP3 inflammasome in the liver. …

… and suppressed the NLRP3 inflammasome activation in … steatosis by inhibiting the NLRP3
inflammasome activation. PTUPB might be a promising potential therapy for liver steatosis …

… that activation of the NLRP3 inflammasome in hepatocytes and liver mononuclear cells …
knockout in NLRP3, ASC, or Caspase-1 developed more severe steatosis and inflammation …

… , IL-18) in the livers of diabetic mice, thus improving NAFLD by … NLRP3 inflammasome
activation in HFD/STZ induced liver … direction for DM combined with NAFLD. Furthermore, trilobatin…

… of absent in melanoma 2 and NLRP3 inflammasomes, leading to the maturation and … liver
inflammation and NAFLD progression. The activity of many inflammasomes involved in NAFLD…

… auranofin can improve NAFLD. Therefore, the purpose of this study is to determine the effect
of auranofin on hepatic steatosis, inflammation and NLRP3 inflammasome, which contribute …

… of the non-alcoholic fatty liver disease; from simple steatosis to … NLRP3 inflammasome and
IL-1β genes in the blood of patients with MAFLD with various degrees of fibrosis and steatosis …

… alleviates hepatocyte steatosis and inhibits the activation of NLRP3 inflammasome in NAFLD.
Our study would try to clarify the role of NLRP3 inflammasome on NAFLD and explore the …