bcl-2 protein in non-small-cell lung carcinoma

F Pezzella, H Turley, I Kuzu, MF Tungekar… - … England Journal of …, 1993 - Mass Medical Soc
… The protein is expressed in basal cells in normal human epithelium, but no data are … in
carcinoma. We studied bcl-2 expression in patients with non-small-cell lung carcinoma and …

Targeted therapy in non-small-cell lung cancer—is it becoming a reality?

F Janku, DJ Stewart, R Kurzrock - Nature reviews Clinical oncology, 2010 - nature.com
… Treatment outcomes in advanced or metastatic non-small-cell lung cancer (NSCLC) remain
unsatisfactory, with low long-term survival rates. Palliative chemotherapy offers a median …

Anaplastic lymphoma kinase inhibition in nonsmall-cell lung cancer

EL Kwak, YJ Bang, DR Camidge… - … England Journal of …, 2010 - Mass Medical Soc
… On the basis of evidence of activity in two patients with nonsmall-cell lung cancer with
ALK … who had nonsmall-cell lung cancer with prospectively identified ALK rearrangement. …

The emerging treatment landscape of targeted therapy in non-small-cell lung cancer

M Yuan, LL Huang, JH Chen, J Wu, Q Xu - Signal transduction and …, 2019 - nature.com
lung cancer. Targeted therapy has emerged as an important mean of the disease management
for patients with non-small-cell lung cancer … clinical trials in lung cancer. Chemotherapy is …

Treatment of stage I non-small cell lung carcinoma

WR Smythe - Chest, 2003 - Elsevier
… The American Joint Committee on Cancer defines stage I non-small cell lung carcinoma (NSCLC)
as consisting of patients with a T1 or T2 primary tumor designation and no evidence of …

Adagrasib in NonSmall-Cell Lung Cancer Harboring a KRASG12C Mutation

PA Jänne, GJ Riely, SM Gadgeel… - … England Journal of …, 2022 - Mass Medical Soc
… ), is the most frequently mutated oncogene in human cancer, with mutations occurring in
approximately 25% of nonsmall-cell lung cancers (NSCLCs). Mutations in KRAS G12C occur …

Immune cell composition in human non-small cell lung cancer

B Stankovic, HAK Bjørhovde, R Skarshaug… - Frontiers in …, 2019 - frontiersin.org
Lung cancer is the leading cause of cancer-related death worldwide with a high annual …
Non-small cell lung cancer (NSCLC) is the most common type of lung cancers, representing ~90…

Targeted therapy for non-small-cell lung cancer: past, present and future

PM Forde, DS Ettinger - Expert review of anticancer therapy, 2013 - Taylor & Francis
… for advanced non-small-cell lung cancer has … on cancer growth. In this comprehensive
review, we look back at developments in targeted therapy for advanced non-small-cell lung cancer

[HTML][HTML] Therapeutic management options for stage III non-small cell lung cancer

SM Yoon, T Shaikh, M Hallman - World journal of clinical oncology, 2017 - ncbi.nlm.nih.gov
Lung cancer is the leading cause of cancer death worldwide. Majority of newly diagnosed
lung cancers are non-small cell lung cancer (NSCLC), of which up to half are considered …

Evolution of systemic therapy for stages I–III non-metastatic non-small-cell lung cancer

JE Chaft, A Rimner, W Weder, CG Azzoli… - Nature reviews Clinical …, 2021 - nature.com
… Systemically, the arsenal of agents used to treat metastatic non-small-cell lung cancer (NSCLC)
has also expanded dramatically with the targeting of mutant oncogenes by tyrosine-…