… to be associated with NAFLD based on case–control studies. … search and review on the
genetic background of NAFLD. … These genetic backgrounds affect the pathology of NAFLD …

… nonalcoholic fatty liver disease (NAFLD) is considered as one of the most significant liver
diseases … , but it is also regulated by genetic background. The role of heritability has been …

… Moreover, genome-wide association studies have discovered several promising candidate
genes, serving as the genetic background for the disease. These genetic players appear to …

In the last three decades the incidence of metabolic syndrome (MetS) has been growing
worldwide along with an increase of obesity, type 2 diabetes mellitus, and non-alcoholic fatty …

… in hepatocytes leading to nonalcoholic fatty liver disease (NAFLD). NAFLD is now present in
around … in ethnic variations of NAFLD, more research focusing on the genetic background of …

… These and other recent findings reviewed here indicate that impaired lipid handling by
hepatocytes has a major role in the pathogenesis of non-alcoholic fatty liver disease by triggering …

… historical data for background. We identified several specific genetic polymorphisms that have
… greatest clinical significance on NAFLD and similar hepatic diseases. These were further …

… To compare the associations of genetics with alcoholic liver disease, we evaluated the
genotype of aldehyde dehydrogenase 2 (ALDH2). ALDH2 is involved in alcohol metabolism, …

… A more complex, yet poorly explored, scenario is the stratification of patients’ response to
medications or lifestyle intervention according to their genetic background. Authors of several …

… steatohepatitis (NASH) to fibrosis and ultimately cirrhosis. Nonalcoholic fatty liver disease is
… not increase hepatic TAG accumulation across a range of dietary and genetic backgrounds. …