The bleeding phenotype in people with nonsevere hemophilia

FR Kloosterman, AF Zwagemaker, CN Bagot… - Blood …, 2022 - ashpublications.org
bleeding phenotype of persons with nonsevere hemophilia and to analyze the association
between baseline factor VIII/IX (FVIII/IX) levels and the joint bleeding … low bleeding frequencies

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B

JM Soucie, PE Monahan, R Kulkarni… - Blood …, 2018 - ashpublications.org
bleeding in hemophilia. We aimed to evaluate associations between hemophilia type and FA
level and joint bleeding … 11-year period on males with nonsevere hemophilia A or B without …

[HTML][HTML] Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile

E Santagostino, ME Mancuso, A Tripodi… - Journal of Thrombosis …, 2010 - Elsevier
… , the severity and frequency of bleeding may be different in hemophiliacs sharing the same
factor activity, a mild bleeding tendency being reported in 10–15% of severe hemophiliacs [1, …

Differences in major bleeding events between patients with severe hemophilia A and hemophilia B: a nationwide, population-based cohort study

MY Shih, JD Wang, JD Yin, YT Tsan… - Clinical and Applied …, 2019 - journals.sagepub.com
… rate and frequency of major bleeding events were similar … mild bleeders with severe
hemophilia could be identified using the endogenous thrombin potential test, and most of these mild

Defining severity of hemophilia: more than factor levels

A Pavlova, J Oldenburg - Seminars in thrombosis and …, 2013 - thieme-connect.com
bleeding into joints or muscles at an early age and bleeding after minimal trauma, whereas
moderate or mild hemophiliacs bleedbleed frequency which suggests a milder bleeding

The factor VIII treatment history of nonsevere hemophilia A

A Abdi, FR Kloosterman, CL Eckhardt… - … of Thrombosis and …, 2020 - Wiley Online Library
… will reduce the bleeding frequency and subsequent FVIII … of patients with non-severe
hemophilia A could provide … given for a bleed was higher in patients with mild hemophilia A when …

[HTML][HTML] Bleeding phenotype in nonsevere hemophilia by International Society on Thrombosis and Haemostasis bleeding assessment tool, bleeding frequency, and …

J Rejtő, D Kraemmer, E Grilz, O Königsbrügge… - Research and Practice …, 2023 - Elsevier
… clinical bleeding phenotype in nonsevere hemophilia and its … such as the onset of bleeding
symptoms and joint impairment … the bleeding phenotype in nonsevere hemophilia on the …

[HTML][HTML] Hemophilia a

BA Konkle - 2017 - europepmc.org
… years; the frequency of bleeding episodes varies… mild hemophilia A do not have spontaneous
bleeding episodes; however, without pre- and postoperative treatment, abnormal bleeding

[HTML][HTML] Hemophilia A and B: molecular and clinical similarities and differences

G Castaman, D Matino - Haematologica, 2019 - ncbi.nlm.nih.gov
… by severe hemophilia. The authors evaluated patients displaying an extremely mild bleeding
… variable severity and frequency of bleeding that patients with hemophilia can experience, …

Analysis of low frequency bleeding data: the association of joint bleeds according to baseline FVIII activity levels

IEM Den Uijl, K Fischer, JG Van Der Bom… - …, 2011 - Wiley Online Library
… The risk for patients with >10% baseline factor level will probably be similar to the curve
shown here, as a large number of patients with mild haemophilia were analysed in this study …