… Sepsis Campaign guidelines provide recommendations for use of norepinephrine as the initial
vasopressor in septic shock … of septic shock but no specific guidance for discontinuation of …

… and pathophysiology of vasopressin and vasopressin receptors, … Vasopressin and Septic
Shock Trial (VASST), a randomized trial of vasopressin versus norepinephrine in septic shock. …

… septic shock, but its effect on mortality is unknown. We hypothesized that low-… vasopressin
as compared with norepinephrine would decrease mortality among patients with septic shock …

… the hypothesis of noninferiority of vasopressin compared to norepinephrine. For the sample
… 75% of patients with septic shock will respond to a single vasopressor; we predicted no …

… among septic shock patients on concomitant norepinephrine (NE) and vasopressin (VP). …
VP (VP DC first) first in septic shock patients. Methods: This retrospective study evaluated …

… Our study is currently the only randomized controlled trial comparing vasopressin to
norepinephrine in severe septic shock. There are only three previously reported clinical studies of …

… to raise MAP or decrease norepinephrine dosage. The purpose of this study was to …
vasopressin to norepinephrine resulted in a reduced time to target MAP compared to norepinephrine …

… to reverse shock. In the landmark, vasopressin in Septic Shock Trial (VASST), vasopressin
deficiency was observed in the early phase of septic shock (3) . Moreover, to achieve the …

… patients are the foundations of septic shock treatment. Recently, early … septic shock
management. However, no particular vasopressor in the early resuscitation phase of septic shock …

… Norepinephrine is the recommended first-line vasopressor 2 but, since a relative vasopressin
deficiency in septic shock was … interest in the use of vasopressin as an adjunctive agent. …