Neurovascular coupling remains unaffected during normal aging

B Rosengarten, C Aldinger, A Spiller… - Journal of …, 2003 - Wiley Online Library
… risk factors were enrolled in this study; they were aged 16.3 ± 3.4 SD years (9 boys), 32.7 ±
2.3 … The neurovascular coupling mechanism seems to be unaffected by moderate aging as …

Neurovascular coupling in normal aging: a combined optical, ERP and fMRI study

M Fabiani, BA Gordon, EL Maclin, MA Pearson… - Neuroimage, 2014 - Elsevier
… was to investigate the effects of aging on neurovascular coupling. As mentioned above, … of
cognitive aging within the brain (for a review, see Kramer et al., 2006). However, aging is also …

Impaired neurovascular coupling in aging and Alzheimer's disease: contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

S Tarantini, CHT Tran, GR Gordon, Z Ungvari… - Experimental …, 2017 - Elsevier
… activation (termed neurovascular coupling or functional … to neurovascular dysfunction and
cognitive decline in aging and in … alterations in neurovascular coupling responses responsible …

BOLD neurovascular coupling does not change significantly with normal aging

J Grinband, J Steffener, QR Razlighi… - Human brain …, 2017 - Wiley Online Library
… healthy aging up to age 75 does not significantly affect the shape of the HRF or the strength
of BOLD neurovascular coupling. The majority of neuroimaging studies of cognitive aging

Assessment of age-related decline of neurovascular coupling responses by functional near-infrared spectroscopy (fNIRS) in humans

T Csipo, P Mukli, A Lipecz, S Tarantini, D Bahadli… - Geroscience, 2019 - Springer
… of the fNIRS approach to measure neurovascular coupling in aging, n = 11 young (32 ± 1.8
years of age, n = 7 males, all participants are right-handed) and n = 13 aged (76 ± 2.17 years …

Age‐related alterations in the cerebrovasculature affect neurovascular coupling and BOLD fMRI responses: Insights from animal models of aging

A Yabluchanskiy, A Nyul‐Toth, A Csiszar… - …, 2021 - Wiley Online Library
Aging is associated with impaired neurovascular coupling responses during increasing
cognitive load. (a) Neural-vascular coupling … impaired neurovascular coupling response in aged

Healthy aging affects cerebrovascular reactivity and pressure-flow responses, but not neurovascular coupling: a cross-sectional study

KB Stefanidis, CD Askew, T Klein, J Lagopoulos… - PLoS …, 2019 - journals.plos.org
… healthy young adults aged 18–30 and older adults aged 60–75, … (MCAv), neurovascular
coupling, cerebrovascular reactivity to … the neurovascular coupling is preserved in healthy aging. …

Age-dependent impairment of neurovascular and neurometabolic coupling in the hippocampus

CF Lourenço, A Ledo, M Caetano, RM Barbosa… - Frontiers in …, 2018 - frontiersin.org
… may underlie the observed neurovascular uncoupling during normal aging, we evaluated
the effect of increasing the oxidative load on neurovascular coupling in young Wistar rats (…

Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease

H Girouard, C Iadecola - Journal of applied physiology, 2006 - journals.physiology.org
… of neurovascular coupling to the health of the normal brain … activity and CBF, termed
neurovascular coupling, is at the basis … summary of neurovascular coupling in the normal state …

Effect of healthy aging on cerebral blood flow, CO2 reactivity, and neurovascular coupling during exercise

D Nowak-Flück, PN Ainslie, AR Bain… - Journal of applied …, 2018 - journals.physiology.org
… to assess whether healthy aging influences the effect of exercise on neurovascular coupling
(NVC) and … Neurovascular coupling and cerebrovascular carbon dioxide reactivity, two key …