… Because of the coexistence of normal brain tissues and tumor cells at tumor brain interface,
… means sacrificing normal brain tissues. Given that localized functions in the brain cannot be …

… The most limiting factor to achieve complete surgical resection is the inability of the surgeon
to distinguish normal brain from tumour cells under normal surgical microscopy. Because of …

… Summary The apoptotic response of normal brain and intracranial VX2 tumour following
photodynamic therapy (PDT) mediated by 5 different photosensitizers (Photofrin, 5-…

… in pathological brain tissue to a higher extent than in normal brain parenchyma (8, 9). …
seems to be a logical concept for brain tumours infiltrating into normal brain (12). Clinical studies …

… In this regard, photodynamic therapy is a viable option to consider, as it aims at treating
infiltrative tumor cells beyond the resection cavity while sparing normal functioning brain. …

… treatment of infiltrative tumor cells into normal brain tissue. Studies indicate that photosensitizers
are accumulating in brain tissue infiltrated by tumor cells and in normal brain tissue [4,9]…

… different photosensitizers for intracranial photodynamic therapy (PDT) of normal brain
tissues and an intracranial tumor was investigated in rabbits, using the photodynamic threshold …

… normal brain. The mean (ram) and sd for the penetration depth of brain, tumour infiltrated brain
… The range of penetration depths for brain, turnout infiltrated brain and tumour alone were …

… uptake into normal brain appears to depend largely upon the intact BBB within normal brain
… Gliomas of increasing grade are associated with increasing destruction of normal brain …

… invasiveness in brain. Because brain injury often induces expression of angiogenic-promoting
molecules, we hypothesize that oxidative insult induced by photodynamic therapy (PDT) …