… the transit of normal surfactant … lung tissue and bronchoalveolar lavage fluid from the patient
supports the idea that the precursor protein was not being processed and secreted normally …

… 26 have demonstrated increased capillary density and angiogenesis in areas of normal lung
flanking regions of fibrosis. The roles of capillary regression and proliferation in contributing …

… The pathologic features of honeycombing, traction bronchiectasis, and fibroblastic foci are
frequently observed in IPF and represent remodeling of the normal lung architecture. Once the …

… In addition to compiling a DNA methylation profile that differentiates IPF patients from normal
individuals, we compared this profile to that of lung adenocarcinoma patients. Our results …

… At the border between fibrotic and normal lung are collections of fibroblasts/myofibroblasts,
termed fibroblastic foci, that are thought to represent the active lesion of UIP (Figure 2) 38. …

… It has been elegantly demonstrated that capillary density is increased in IPF lungs in
areas of minimal fibrosis or normal lung tissue, whereas it is decreased in the most extensive …

… Hallmark findings of UIP are noted, including areas of dense fibrosis (white arrow) adjacent
to areas of normal lung (striped arrow), fibroblastic foci (black arrow) and hyperplastic …

… However, as noted by Mishra and colleagues, p53 is expressed during normal wound
healing (29). What differentiates normal lung repair from abnormal scar formation is still under …

… . Different expression of TNF-alpha receptors and prostaglandin E(2) production in normal
and fibrotic lung fibroblasts: potential implications for the evolution of the inflammatory process…

… Thus, the lung volumes and spirometric values may seem surprisingly normal in a smoker
with pulmonary fibrosis who is experiencing severe exertional dyspnea. In this situation, the …