In vitro bactericidal activity of human β-defensin 2 against nosocomial strains

JG Routsias, P Karagounis, G Parvulesku, NJ Legakis… - Peptides, 2010 - Elsevier
Human β-defensin 2 (hBD-2) is a 41-amino acid cationic peptide of the innate immune system
that serves as antimicrobial molecule. We determined the bactericidal activity of synthetic …

In vitro bactericidal activity of human β-defensin 3 against multidrug-resistant nosocomial strains

G Maisetta, G Batoni, S Esin, W Florio… - Antimicrobial agents …, 2006 - Am Soc Microbiol
… A fast bactericidal effect (within 20 min) against all bacterial strains tested was observed. The
… gram-negative strains and reduced the activity of the peptide against gram-positive strains. …

Activity of human β-defensins 2 and 3 against ESBL-producing Klebsiella strains

H Sahly, S Schubert, J Harder, M Kleine… - Journal of …, 2006 - academic.oup.com
… the Center for Disease Control criteria for nosocomial pneumonia, urinary tract infection,
primary … of each strain was noted and only one strain per patient was included. The strains were …

[HTML][HTML] ß-defensin-2 in breast milk displays a broad antimicrobial activity against pathogenic bacteria

J Baricelli, MA Rocafull, D Vázquez, B Bastidas… - Jornal de …, 2015 - SciELO Brasil
… of human-defensin-2 against enteropathogens and nosocomial strains has been reported.
26… In vitro bactericidal activity of human beta-defensin 2 against nosocomial strains. Peptides. …

New role for human α-defensin 5 in the fight against hypervirulent Clostridium difficile strains

L Furci, R Baldan, V Bianchini, A Trovato… - Infection and …, 2015 - Am Soc Microbiol
… Clostridium difficile infection (CDI), one of the most common hospital-acquired infections, is
increasing in incidence and severity with the emergence and diffusion of hypervirulent strains

Microbicidal effects of α- and θ-defensins against antibiotic-resistant Staphylococcus aureus and Pseudomonas aeruginosa

KP Tai, K Kamdar, J Yamaki, VV Le, D Tran… - Innate …, 2015 - journals.sagepub.com
… (PA) is a leading cause of nosocomial infections for which the fluoroquinolone antibiotics, for
… epithelial cells, and we compared strain α-defensin susceptibility to cytotoxic potential. For …

Human β-defensin 3 inhibits antibiotic-resistant Staphylococcus biofilm formation

C Zhu, H Tan, T Cheng, H Shen, J Shao, Y Guo… - journal of surgical …, 2013 - Elsevier
… As an opportunistic human pathogen, Staphylococcus strains have recently become the
most important cause of nosocomial infections and are one of the major pathogens in implant-…

[HTML][HTML] The human beta-defensin-3, an antibacterial peptide with multiple biological functions

V Dhople, A Krukemeyer, A Ramamoorthy - Biochimica et Biophysica Acta …, 2006 - Elsevier
… show antimicrobial activities against Gram-negative and Gram-positive bacterial strains
and … -resistant clinical isolates of common nosocomial pathogens, such as Staphylococcus …

Applications of β-defensins against infectious pathogenic microorganisms

X Li, X Wang, J Du, X Bu, C Peng… - Expert Review of Anti …, 2024 - Taylor & Francis
… as β-defensins. This review provides a comprehensive analysis of the effects of β-defensins
The lack of effective drugs for antimicrobial-resistant strains highlights the urgent need to …

β-defensins: work in progress

G Donnarumma, I Paoletti, A Fusco, B Perfetto… - … Infectious Diseases and …, 2016 - Springer
… The strain adheres to A549 cell monolayers with the same efficiency when challenged at
28 C or 37 C, and stimulates innate immune responses releasing β defensin 2 and forming a …