Genetic variations and epigenetic modulations in CYP genes: Implications in NSAID-treatment of arthritis patients
SR Chowdhury, OD Gupta, AK Ghosh, PS Singha… - The Nucleus, 2021 - Springer
… There are several reports indicating epigenetic regulation of the CYP … NSAID treated patients
with genetic polymorphism. In this review, complications associated with the use of NSAIDs …
with genetic polymorphism. In this review, complications associated with the use of NSAIDs …
[HTML][HTML] The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation
HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
… , at the genomic level, with TLR4 signaling and modulating miRNA upregulation after NF-κB …
and epigenetic modulation. In brief, we considered three main epigenetic processes of gene …
and epigenetic modulation. In brief, we considered three main epigenetic processes of gene …
Epigenetic modulation of the immune function: a potential target for tolerance
B Suárez-Álvarez, A Baragaño Raneros, F Ortega… - Epigenetics, 2013 - Taylor & Francis
… Epigenetic modifiers, such as histone deacetylase (HDAC) inhibitors have considerable
potential as anti-inflammatory … Moreover, the detection of epigenetic marks in key immune genes …
potential as anti-inflammatory … Moreover, the detection of epigenetic marks in key immune genes …
Epigenetic regulation of airway inflammation
… Anti-microbial gene promoters retain the epigenetic marks that prime cells to respond to
subsequent LPS stimulation, whereas anti-inflammatory gene promoters lose their histone …
subsequent LPS stimulation, whereas anti-inflammatory gene promoters lose their histone …
Interaction of a common painkiller piroxicam and copper-piroxicam with chromatin causes structural alterations accompanied by modulation at the epigenomic …
… of a traditional NSAID, piroxicam [Px] belonging to the oxicam NSAIDs and its copper …
Our results clearly indicate that treatment with [Cu(II)-(Px) 2 (L) 2 ] alters selective epigenetic …
Our results clearly indicate that treatment with [Cu(II)-(Px) 2 (L) 2 ] alters selective epigenetic …
Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation
L Bäckdahl, A Bushell, S Beck - The international journal of biochemistry & …, 2009 - Elsevier
… epigenetic modulation remains poorly understood. Here, we review recent progress and
discuss key factors driving epigenetic modulation … redundant internal anti-inflammatory pathway. …
discuss key factors driving epigenetic modulation … redundant internal anti-inflammatory pathway. …
Inflammation and epigenetic regulation in osteoarthritis
… epigenetic modifications of pro- and anti-inflammatory signatures occur, leading to acute
inflammation at initial stages of the response followed by epigenetic … In addition, modulation of …
inflammation at initial stages of the response followed by epigenetic … In addition, modulation of …
Role of epigenetics in inflammation-associated diseases
MK Shanmugam, G Sethi - Epigenetics: Development and disease, 2012 - Springer
… Thus, the focus of the current chapter is to highlight the evidences that epigenetic modulation
… In addition, synthetic histone mimetic I-BET showed anti-inflammatory activity by interfering …
… In addition, synthetic histone mimetic I-BET showed anti-inflammatory activity by interfering …
Epigenetic mechanisms in inflammation
D Bayarsaihan - Journal of dental research, 2011 - journals.sagepub.com
… known about the epigenetic pathways involved in the modulation of inflammatory and anti-inflammatory
genes. This review summarizes the current knowledge about epigenetic control …
genes. This review summarizes the current knowledge about epigenetic control …
[HTML][HTML] Epigenetic regulation of inflammatory signaling and inflammation-induced cancer
SYX Tan, J Zhang, WW Tee - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
… epigenetic alterations and inflammation, as well as highlight the therapeutic application of
anti-inflammatory and epigenetic … Epigenetic modulations can also be actuated by hormonal …
anti-inflammatory and epigenetic … Epigenetic modulations can also be actuated by hormonal …
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