Polymorphisms of the neurotrophic factor-3 (NTF-3) in Alzheimer's disease: rs6332 associated with onset time and rs6489630 T allele exhibited a protective role

M Liu, YR Huo, J Wang, S Liu, S Liu… - Journal of …, 2015 - Taylor & Francis
… function in Alzheimer’s disease (AD), neurotrophin-3 (NTF-3) … and rs6332) within the NTF-3
gene have been associated … of this finding, we analyzed the NTF-3 polymorphism in a Han …

Genetic association between neurotrophin-3 polymorphisms and Alzheimer's disease in Japanese patients

T Nagata, N Shibata, S Shinagawa… - Dementia and Geriatric …, 2013 - karger.com
… for Alzheimer’s disease (AD). In the present study, we examined whether neurotrophin-3 (NTF-3) …
We identified 3 representative NTF-3 single nucleotide polymorphisms (SNPs): rs6332, …

Neurotrophic factors in Alzheimer's disease: role of axonal transport

K Schindowski, K Belarbi, L Buee - Genes, brain and behavior, 2008 - Wiley Online Library
… with imbalanced distribution and dysregulation of NTF. In particular, brain-… diseases.
Here, we review the changes of NTF expression and distribution (NGF, BDNF, neurotrophin-3, …

Therapeutic potential of neurotrophic factors in Alzheimer's Disease

A Nasrolahi, F Javaherforooshzadeh… - Molecular biology …, 2022 - Springer
Alzheimer's disease (AD) is a progressive … effects of NTFs delivery in humans limit the
efficacy of NTFs therapy in … The results of this study indicated that NT-3 gene transfection could …

Neurotrophic factors in Alzheimer's and Parkinson's disease brain

GJ Siegel, NB Chauhan - Brain Research Reviews, 2000 - Elsevier
… factors (NTF) and their receptors in Alzheimer’s disease (AD) and Parkinson’s disease (PD)
brain and … NT-3 levels have been determined in various portions of human brain [208] while …

Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains

N Durany, T Michel, J Kurt, FF Cruz-Sánchez… - International Journal of …, 2000 - Elsevier
… The administration of NTFs to AD patients has been suggested in order to attenuate the rate
… can consider the application of NTFs as therapeutic agents in neurodegenerative diseases. …

[HTML][HTML] BARHL1 is downregulated in Alzheimer's disease and may regulate cognitive functions through ESR1 and multiple pathways

D Barh, ME García-Solano, S Tiwari, A Bhattacharya… - Genes, 2017 - mdpi.com
… are described in Table 3. From this network, we observed that Neurotrophin 3 (NTF3) probably
… in our expression studies), both the NTF3- and BDNF-mediated neurogenesis and neural …

Neurotrophin growth factors and their receptors as promising blood biomarkers for Alzheimer's Disease: a gene expression analysis study

MR Asadi, J Gharesouran, H Sabaie… - Molecular Biology …, 2024 - Springer
… For example, the TrkA receptor attaches to NGF and regulates neuronal survival and
differentiation in the PNS, while the TrkB and TrkC receptors bind to BDNF and NTF3/4, respectively…

Neurotrophic factors in Alzheimer's disease: Pathogenesis and therapy

J Lübke, F Idoon, M Mohasel‑Roodi, F Alipour… - Acta Neurobiologiae …, 2021 - ane.pl
… , NTF treatment may be a good candidate for de‑ laying several neurodegenerative diseases
… This review aimed to provide the pharmacological basis for clinical usage of NTFs in the …

[HTML][HTML] Homodimerization of presenilin N-terminal fragments is affected by mutations linked to Alzheimer's disease

S Cervantes, R Gonzàlez-Duarte, G Marfany - FEBS letters, 2001 - Elsevier
NTF and CTF homodimerization, we propose the contribution of two NTFs and two CTFs,
instead of a single NTF:… control); lanes 3 and 4: yeast expressing the PSN NTF-Cub-ProtA-LexA-…