… cell-based studies of the SUN-KASH complex. We observed a 3:3 ratio in the hexameric
SUN-KASH complex in which the SUN domain trimer binds three separate KASH peptides. Our …

… SUN-KASH interfaces function in LINC complex assembly and force transmission at the
nuclear envelope… Each panel shows a cartoon simulation focusing on the SUN-KASH interface. …

… of conserved SUN–KASH bridges, or LINC complexes, that span the nuclear envelope. Recent
… targeting of SUN proteins to the inner nuclear membrane. Structural studies characterize …

… SUN Proteins Our current understanding of the molecular mechanisms of the SUN-KASH
nuclear-envelope … TorsinA at the nuclear envelope displaces KASH-SUN complexes and alters …

… complexes (LINC complexes) and are formed by the interaction of SUN and KASH domain
proteins in the nuclear envelope. Ample evidence suggests that SUN–KASH complexes form …

… SUN/KASH bridges are not required to maintain even nuclear envelope spacing in most …
to determine if LINC complexes play a role in stabilizing the nuclear envelope space in regions …

… LINC complexes are formed by trans-luminal interactions between inner nuclear membrane
SUN proteins and outer nuclear membrane KASH proteins, but how these interactions are …

… at the NE, nuclear shape determination, nuclear positioning, anti-… current understanding of
plant SUN, KASH, and other related … The SUN–WIP complex plays a role in maintaining the …

… Next we discuss the various types of mechanical loading that is experienced by the nuclear
envelope through LINC complexes during various cellular processes. Finally, we survey …

… complex is found in a wide variety of organisms and is formed by the transluminal interaction
between outer- and inner-nuclear-membrane KASH and SUN … imply that the KASH binding …