… The first decade of 3C methods rendered unprecedented insights into genome topology.
Here… We explain how more detailed insights into the 3D genome increase our understanding of …

… Interest in nuclear structure was further fueled by the realization that the nucleus contains …
systematic and detailed analysis of nuclear organization. Traditionally, nuclear organization is …

… Prospectively, these structural insights might trigger novel types of investigations that will
shed light on the mechanism behind nucleocytoplasmic transport (as well as other functions of …

… that have provided exciting insight into the interplay between nuclear architecture, genome
… Here we discuss the dynamics and plasticity of nuclear organization in ES cells and early …

… then detail some of the key mechanistic findings about nuclear … implicated nuclear size in
the regulation of cell and nuclear … of nuclear size in chromatin organization, gene expression, …

… in the functional architecture of the nucleus, revealing surprising and novel findings about
nuclear organization and functions beyond that of being a mere repository of the genome. …

… Cryo-ET has provided an insight into the structure of lamin filaments, but its restricted field
of view does not allow the study of the entire organization of the mammalian nuclear lamina. A …

… and between nuclear organizations. Considering learning processes at the level of the nuclear
… transfer of knowledge between organizations, rather than on learning dynamics within an …

… Knowing this may provide important insights into the mechanisms of Polycomb-mediated …
An observation more fundamental to understanding the nuclear organization of transcription is …

… , biochemical tools decipher nuclear organization by measuring physical contacts between
different genomic regions or between genomic DNA and other nuclear components. Initially …