… view of its central core and revealed that an unexpected network of short linear motifs is an
… properties, for example, affinity to binding sites offered by the scaffold proteins, and thus are …

… transport are regulated at multiple stages, and the NPC carries binding sites for many of …
unexpected aspects about the NPC and its interacting transport factors. Perhaps most surprising …

… and cytoplasmic compartments of the eukaryotic cell are separated by a double-membraned
nuclear envelope (NE). Nuclear pore complexes (NPCs) provide the only known sites for …

… In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that
NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in …

… the nucleus and the … the nuclear pore complex (NPC) has been presented as a static channel
through which dynamic transport receptor-cargo complexes traverse the nuclear envelope. …

… Because mapping of the individual components in the Nup84 complex places Nup120 and
… continue to provide unexpected and spectacular insight into the complex architecture of the …

… Nuclear pore complexes are large aqueous channels that penetrate the nuclear envelope,
thereby connecting the nuclear … Until recently, these macromolecular complexes were viewed …

… nuclear pore complex consists of four separate structural elements: (a) the scaffold, which
includes the majority of the pore as … one of the most active areas of interest in nuclear transport. …

… is the nuclear pore complex (NPC), an ∼50 MDa assembly comprised of ∼30 different
proteins called Nups that mediates selective macromolecular transport between the nucleus and …

… nucleoplasm, merely providing static binding sites for rapidly trafficking transport receptors.
… An average residence time of about 5 min was observed for gp210, which was surprising as …