Molecular beacons: a novel DNA probe for nucleic acid and protein studies

W Tan, X Fang, J Li, X Liu - Chemistry–A European Journal, 2000 - Wiley Online Library
Molecular beacons are single-stranded oligonucleotides that possess a stem-and-loop … of
the molecular beacons can report the presence of a specific complementary nucleic acid. The …

Molecular beacons

W Tan, K Wang, TJ Drake - Current opinion in chemical biology, 2004 - Elsevier
molecular beacon structural conformation changes in the presence of both proteins and nucleic
acids… stems in the presence of target nucleic acids. Two complementary sticky ends from …

Quencher-free molecular beacons: a new strategy in fluorescence based nucleic acid analysis

N Venkatesan, YJ Seo, BH Kim - Chemical Society Reviews, 2008 - pubs.rsc.org
… In summary, we have illustrated that quencher-free molecular beacons (QF-MBs) play a
significant role in nucleic acid analysis. The QF-MBs are designed mainly for sensitive …

Molecular beacons: colorful analysis of nucleic acids

JAM Vet, BJMV Rijt, HJ Blom - Expert review of molecular …, 2002 - Taylor & Francis
… of the exciting applications of molecular beacons in DNA, RNA and protein studies. …
Molecular beacons can also be used in assays that employ isothermal nucleic acid amplification …

Real-time investigation of nucleic acids phosphorylation process using molecular beacons

Z Tang, K Wang, W Tan, C Ma, J Li, L Liu… - Nucleic acids …, 2005 - academic.oup.com
… Phosphorylation of nucleic acids is an indispensable process to repair strand interruption
of nucleic acids. We have studied the process of phosphorylation using molecular beacon (MB…

Real-time assays with molecular beacons and other fluorescent nucleic acid hybridization probes

SAE Marras, S Tyagi, FR Kramer - Clinica Chimica Acta, 2006 - Elsevier
… To demonstrate the use of molecular beacons in extremely sensitive, high-throughput,
clinical tests, an assay was developed for the detection of retroviral nucleic acids in blood …

Monitoring nucleic acids using molecular beacons

CJ Yang, CD Medley, W Tan - Current pharmaceutical …, 2005 - ingentaconnect.com
Molecular beacons can be used to monitor the dynamics of mRNA in living cells and reveal
the response of gene expression to external stimuli, such as drug molecules, hormones, …

Locked nucleic acid molecular beacons

L Wang, CJ Yang, CD Medley… - Journal of the …, 2005 - ACS Publications
… , and investigated a novel molecular beacon (MB) using locked nucleic acid (LNA) bases. …
One such probe is the molecular beacon (MB), 1 a short hairpin oligonucleotide probe that …

[HTML][HTML] Molecular beacons of xeno-nucleic acid for detecting nucleic acid

Q Wang, L Chen, Y Long, H Tian, J Wu - Theranostics, 2013 - ncbi.nlm.nih.gov
Molecular beacons (MBs) of DNA and RNA have aroused increasing interest because they
allow a continuous readout, excellent spatial and temporal resolution to observe in real time. …

Molecular beacons: probes that fluoresce upon hybridization

S Tyagi, FR Kramer - Nature biotechnology, 1996 - nature.com
… We have developed novel nucleic acid probes that recognize and report the presence of …
Results Design and construction of molecular beacons. We prepared two molecular beacons